Results 51 to 60 of about 2,815,885 (243)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Fashioning liminal space : the meaning of things and women's experience in the practice of domestic shrine making in Aotearoa/New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Social Anthropology at Massey University [PDF]

open access: yes, 2003
This paper aims to bring together two lines of analysis that converge upon the specific spaces that are women's domestic shrines. One line examines the material culture of the spaces and objects on the shrines of ten different women and seeks to reveal ...
Savage, Deirdre Anne
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Employing Psychoacoustics in Sensory Archaeology: Developments at the Ancient Sanctuary of Zeus on Mount Lykaion

open access: yesOpen Archaeology, 2023
Psychoacoustics offers a promising, subject-centred approach in unlocking the sonic experience of past built spaces. Its tools and metrics offer tempting responses to an essential challenge of sensory archaeology practice: the rendition of individual ...
Jordan Pamela
doaj   +1 more source

Lessons from Love-Locks: The archaeology of a contemporary assemblage [PDF]

open access: yes, 2017
This document is the Accepted Manuscript version. The final, definitive version of this paper has been published in Journal of Material Culture, November 2017, published by SAGE Publishing, All rights reserved.Loss of context is a challenge, if not the ...
Bord J   +31 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An experience of application of experimental-traceological analysis to ethnographic collections (the example of the ulu-knife of the Alutiiq Eskimos from Kodiak Island) [PDF]

open access: yesВестник археологии, антропологии и этнографии
The article presents the results of a comprehensive analysis of an ulu-knife (uluchik) from the ethnographic collection of I.G. Voznesensky of the Alutiiq Eskimos from the island of Kodiak (MAE No. 593-44).
Terekhina V.V.
doaj   +1 more source

Changing Practice in a National Legal Deposit Library [PDF]

open access: yes, 2006
This two-part essay considers how digital culture has influenced ideas about permanence and looks at the change in collecting practice in a legal deposit library.
Mason, Ingrid
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Towards an Archaeology of the Contemporary Past [PDF]

open access: yes, 2002
Archaeology, defined as the study of material culture, extends from the first preserved human artefacts up to the present day, and in recent years the ‘Archaeology of the Present’ has become a particular focus of research.
Buchli, V
core  

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