Results 91 to 100 of about 287,684 (305)
Transactions of the Association of European Schools of Planning, 2018 Planning research frequently deals with issues of transition. Transition is defined here broadly as the change of social and spatial state from the one position into another.
Willem Salet
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Supporting reinterpretation in computer-aided conceptual design [PDF]
, 2008 This paper presents research that aims to inform the development of computational tools that better support design exploration and idea transformation - key objectives in conceptual design.
AHRC (Funder) +7 more
core
EnergiesAn electrochemical reactions coupled multi-physics model is developed and applied to elucidate overall performance and thermal stress distributed in solid oxide electrolysis cells (SOECs) with graded fuel electrodes.
Fangzheng Liu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Recognizing the Enemy: Rap Music In the Wake of the Los Angeles Riots [PDF]
, 1993 The May 1992 riots in Los Angeles demonstrated more than anything in recent history that the inner cities are filled with despair, hopelessness, and anger. Some feel that rap music is responsible for both gangs and the lawlessness unleashed by the riots.
Martinez, Theresa A.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
ASIAN AMERICANS IN PSYCHIATRIC SYSTEMS [PDF]
, 1979 Prior to the l960\u27s, very little interest had been shown in researching patterns of American utilization of mental health facilities. The notion of culturally different patterns of psychological “normalcy” for Asian Americans as a distinct population ...
Tashima, Niel
core +1 more source
Young children explore: critical thinking for the Early Years [PDF]
, 2014 Dr Jane Murray explains how her PhD research can help practitioners recognise and evaluate young children's explorations as critical ...
Murray, Jane
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source