Results 121 to 130 of about 286,454 (307)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
[Review of] Philip Durham and Everett L. Jones. The Negro Cowboy [PDF]
, 1991 Except for books such as The Negro Cowboys, the African American West remains an enigma to most Americans. Popular media continue to perpetuate the stereotype of a white West, in spite of the fact that some of the earliest explorers accompanying the ...
Junne, George H., Jr.
core +1 more source
NGI Explorers Mission 1 material
, 2021 NGI Explorers Mission 1 material: video interviews, Mentorship groups and Bootcamp ...
openaire +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Frozen in Place: European American Ideologies and the Inuit [PDF]
, 1994 It has been claimed by Hugh Brody that European Americans maintain strong ideological connections between Inuit people and the Arctic environments they inhabit.
Buege, Douglas J.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The design and use of eActivities for learning mathematics [PDF]
, 2004 The recent development by Casio of the hand-held ClassPad 300 device raises a number of important questions for the design of mathematical learning experiences for students. This paper provides a brief description of the ClassPad 300 and its mathematical
Kissane, B.
core +1 more source