Results 61 to 70 of about 9,803,493 (256)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Cleaner Production LettersThe Circular Economy has emerged as a key strategy for reducing resource consumption and environmental impacts across industries, and understanding the end-of-life processes of products is essential in this transition.
Carolin Escherich +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Transmission loss predictions for dissipative silencers of arbitrary cross section in the presence of mean flow [PDF]
, 2003 A numerical technique is developed for the analysis of dissipative silencers of arbitrary, but axially uniform, cross section. Mean gas flow is included in a central airway which is separated from a bulk reacting porous material by a concentric ...
Kirby, R, Ray Kirby
core +1 more source
EnergiesMultiple minor text corrections were made to the original publication [...]
Niklas Scholliers +4 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Subscale modeling of material flow in orthogonal metal cutting [Elektronisk resurs]
Enhanced simulation capability for the cutting process is crucial to making quick evaluations of cutting forces and temperatures, which are significant for assessing the machinability of the workpiece material and predicting tool wear. In this paper, the
Larsson, Ragnar,, Ertürk, Ahmet Semih,
core +1 more source
EnergiesDistrict heating networks (DHNs) are a key technology in the transition toward sustainable heat supply, increasingly integrating renewable sources and thermal energy storage.
Niklas Scholliers +4 more
doaj +1 more source