Results 81 to 90 of about 9,803,493 (256)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Material Flow Accounting of Mexico (1970-2003). Sources and Methods [PDF]
This technical background paper describes the methods applied and data sources used in the compilation of the 1980-2003 data set for material flow accounts of the Mexican economy and presents the data set.
Ana Citlalic González Martínez
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Five Facts About Quick Flow That Will Blow Your Mind.
, 2021 Reduced levels of the male hormone, testosterone, and an interrupted blood flow to most of the organs of the body produce abnormal growth and hinder the absorption of nutrients required for proper development. One such effect of these disorders is highly
Quick Flow
core +1 more source
Consequential life cycle assessment of demolition waste management in Germany
Frontiers in SustainabilityContextBulk mineral waste materials such as construction and demolition waste are Germany’s largest waste stream. Despite the availability of high-quality recycling pathways such as road base layers, waste concrete is predominantly recycled into lower ...
Christian Dierks +4 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Resource Prospects of Municipal Solid Wastes Generatedin the Ga East Municipal Assembly of Ghana
Journal of Health and Pollution, 2017 Background. Municipal solid wastes management has recently become an important public health concern. Municipal solid wastes are a major source of raw materials that could be used for resource recovery for diverse applications. Objectives.
Benedicta Abiti +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Importance of Material Flow Analysis for Commodity Transport Demand and Modelling [PDF]
It can be shown that generated and attracted transport volumes, measured in tons, are closely related to direct material input (DMI). However, structural changes and new logistics concepts still lead to an increase of transportation performance ...
Gernot T. Liedtke +3 more
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