Results 41 to 50 of about 373,182 (301)
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
We research the non-linear eigenvalues problem which appears from the problem of determining the stress-strain state near the transverse shear crack tip in material with power relationship between strains and stresses.
L. V. Stepanova, M. E. Fedina
doaj +1 more source
Non-linear Hall effects: Mechanisms and materials
This review presents recent breakthroughs in the realm of nonlinear Hall effects, emphasizing central theoretical foundations and recent experimental progress. We elucidate the quantum origin of the second-order Hall response, focusing on the Berry curvature dipole, which may arise in inversion symmetry broken systems.
Arka Bandyopadhyay +2 more
openaire +3 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Charged Pion Energy Reconstruction in the ATLAS Barrel Calorimeter [PDF]
The intrinsic performance of the ATLAS barrel and extended barrel calorimeters for the measurement of charged pions is presented. Pion energy scans (E = 20, 50, 200, 400 and 1000 GeV) at two pseudo-rapidity points ($\eta$ = 0.3 and 1.3) and ...
Bosman, M., Kulchitsky, Y., Nessi, M.
core +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Non-linear buckling analysis of functionally graded shallow spherical shells
In the present paper the non-linear buckling analysis of functionally graded spherical shells subjected to external pressure is investigated. The material properties are graded in the thickness direction according to the power-law distribution in terms ...
Dao Huy Bich
doaj +1 more source
High frequency electro-optic measurement of strained silicon racetrack resonators
The observation of the electro-optic effect in strained silicon waveguides has been considered as a direct manifestation of an induced $\chi^{(2)}$ non-linearity in the material.
Bernard, M. +7 more
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Response Surfaces in the Numerical Homogenization of Non-Linear Porous Materials
The paper deals with the numerical homogenization of structures made of non-linear porous material. Material non-linearity causes a significant increase in computational costs for numerical homogenization procedure. An application of the response surface
Witold BELUCH, Marcin HATŁAS
doaj +1 more source

