Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
MOF-derived MoO<sub>2</sub>/C composites as high-performance electrodes for electrochemical uranium(vi) removal. [PDF]
Zhou H, Jiao R, Ma X, Zeng S, Mi Y.
europepmc +1 more source
Data-driven material removal rate estimation in bonnet polishing process
Michal Darowski +4 more
openaire +1 more source
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source
Influence of HFCVD Parameters on Diamond Coatings and Process Investigation of Sapphire Wafer Lapping. [PDF]
Feng W, Zhou S, Sun X.
europepmc +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Fabrication of a ZGTPM nanocomposite membrane for the synergistic removal of tetracycline via size selective sieving and photocatalytic degradation. [PDF]
El-Sawaf AK +5 more
europepmc +1 more source
EXPERIMENTAL STURY OF MATERIAL REMOVAL RATE FOR ELECTRICAL DISCHARGE MACHINING
openaire +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source

