Results 51 to 60 of about 122,093 (306)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

IMPLEMENTASI MATERIAL REQUIREMENTS PLANNING (MRP) PADA PERENCANAAN PERSEDIAAN MATERIAL PANEL LISTRIK DI PT.TIS

Jurnal Ilmiah SINERGI, 2016
Semakin berkembangnya dunia industri perusahaan manufaktur membuat semakin ketatnya  persaingan pasar untuk mencukupi kebutuhan konsumen. Selain itu perusahaan juga dituntut untuk dapat memuaskan konsumen dengan cara  menyelesaikan pesanan konsumen tepat
Putri Sari Dewi, Dana Santoso Saroso
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Strategies for integrated management -material requirements planning

, 2017
Implementacja w przedsiębiorstwach nowoczesnych rozwiązań informatycznych w celu usprawnienia zarządzania to warunek sukcesu przedsiębiorstwa w dobie globalizacji.
Witczyńska, K.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

BIM-Based Automatic Extraction of Daily Concrete and Formwork Requirements for Site Work Planning

Buildings
Material planning is important in construction, for it affects procurement, cost, and schedule. Proper planning of material supply and logistics helps streamline the performance of all tasks through the avoidance of excessive or insufficient material ...
Van-Hoan Pham, Po-Han Chen, Quan Nguyen, Diep-Thuy Duong   +3 more
doaj   +1 more source

Generative Design In Factory Layout Planning: An Application Of Evolutionary Computing Within The Creation Of Production Logistic Concepts

Proceedings of the Conference on Production Systems and Logistics, 2020
This paper describes the creation and application of a generative design approach in the production logistics layout concept creation as part of factory planning projects.
Dannapfel, Matthias, Vierschilling, Sebastian Patrick, Losse, Stephan, Matzke, Oliver   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Demand Driven Material Requirements Planning

, 2020
Manufacturing industries used to develop their operation strategies focusing on the cost of manufacturing, high volume production, and stabilizing the customer demand.
Arakatla, Adarsh
core  

PENERAPAN METODE MATERIAL REQUIREMENTS PLANNING UNTUK PERBAIKAN PENGADAAN MATERIAL DI PT DELIDENT CHEMICAL INDUSTRY LTD [PDF]

, 2001
PENERAPAN METODE MATERIAL REQUIREMENTS PLANNING UNTUK PERBAIKAN PENGADAAN MATERIAL DI PT DELIDENT CHEMICAL INDUSTRY ...
YUNITA, YULIANA
core