Results 61 to 70 of about 9,102,254 (281)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Measuring the strength of brittle materials by depth-of-penetration testing [PDF]
Based on an energy conservation model, the strength offered by a number of brittle materials has been calculated from depth-of-penetration (DOP) test results. Each material was completely penetrated by a tungsten carbide cored projectile of known kinetic
Hazell, Paul J., P J Hazell
core +1 more source
Bridge stay cables play a vital and indispensable role in the structural integrity and safety of cable-supported bridges. Statistical data indicates that nearly 100% of bridge stay cables exhibit varying degrees of damage, with corrosion being the most ...
ZHU Fei +5 more
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
FRICTION STIR PROCESSING OF THE CAST ALUMINUM ALLOY EN AW 5083 (AlMg4,5Mn0,7)
The paper presents the analysis of the behavior of the cast aluminum alloy EN AW 5083 (AlMg4,5Mn0,7) to the friction stir processing (FSP), which is applied in order to locally modify some properties / characteristics of the base material.
Lia Nicoleta Botila +2 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Repetitive Availability Demonstration Testing Procedure
The proposed availability demonstration test (ADT) is an extension of the work of Usher and Taylor [Usher, J.S. and Taylor, G.D., "Availability Demonstration Testing," Qual. Reliab. Eng. Int., Vol. 22, No. 4, 2006, pp.
Usher, J. S. +3 more
core +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source

