Results 71 to 80 of about 9,102,254 (281)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A custom-built planar biaxial system for soft tissue material testing. [PDF]

open access: yesHardwareX, 2023
Pasta S   +3 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Proceedings of the 1966 invitational conference on testing problems

open access: yes, 1966
La couv.
Educational Testing Service Invitational Conference on Testing Problems. Proceedings (1966 : New York)
core   +1 more source

A subset of precise UML for Model-based Testing [PDF]

open access: yes, 2007
This paper presents an original model-based testing approach that takes a UML behavioural view of the system under test and automatically generates test cases and executable test scripts according to model coverage criteria.
Legeard, B   +19 more
core   +1 more source

RESEARCH ON SUBMERGED FRICTION STIR PROCESSING OF EN AW 6082 ALUMINUM ALLOY

open access: yesNonconventional Technologies Review
Submerged friction stir processing (SFSP) is a variant of processing the surfaces of metallic materials that uses the liquid medium to ensure a process temperature that does not thermally overload the materials to be processed or the processing tool ...
Lia Nicoleta Botila   +3 more
doaj  

Design, printing optimization, and material testing of a 3D-printed nasal osteotomy task trainer. [PDF]

open access: yes3D Print Med, 2023
Schlegel L   +8 more
europepmc   +1 more source

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