Results 91 to 100 of about 1,702,166 (311)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Phase Transformations in Nickel base Superalloy Inconel 718 during Cyclic Loading at High Temperature

Production Engineering Archives, 2017
Nickel base superalloys are hi-tech materials intended for high temperature applications. This property owns a complex microstructure formed by matrix of Ni and variety of precipitates.
Michal Jambor, Otakar Bokůvka, František Nový, Libor Trško, Juraj Belan   +4 more
doaj   +2 more sources

High performance polymer development [PDF]

The term high performance as applied to polymers is generally associated with polymers that operate at high temperatures. High performance is used to describe polymers that perform at temperatures of 177 C or higher.
Hergenrother, Paul M.
core   +1 more source

Combustion method for assay of biological materials labeled with carbon-14 or tritium, or double-labeled [PDF]

, 1969
Dry catalytic combustion at high temperatures is used for assaying biological materials labeled carbon-14 and tritium, or double-labeled. A modified oxygen-flask technique is combined with standard vacuum-line techniques and includes convenience of ...
Huebner, L. G., Kisieleski, W. E.
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Oxidation behavior of powder metallurgy processed AlCrNiFeMnWx tungsten-containing high-entropy alloys at isothermal temperatures

Journal of Materials Research and Technology
Developing materials with outstanding oxidation resistance and structural stability is essential for applications where mainly exposed to temperatures. In this context, tungsten (W) is renowned for its ability to form stable, protective oxide layers at ...
Sheetal Kumar Dewangan, Cheenepalli Nagarjuna, Hansung Lee, Eunhyo Song, Vinod Kumar, Byungmin Ahn   +5 more
doaj   +1 more source

Research on materials for advanced electronic and aerospace application [PDF]

Research data are reported on optical and magnetic data processing, hydrogen in metals and stress corrosion phenomena, and polymers and materials at high temperatures and ...

core   +1 more source

Prediction of elasticity characteristics for the unidirectional polymer composite materials at high temperatures [PDF]

, 2016
Досліджується ефективність прогнозування характеристик пружності односпрямованих полімерних композиційних матеріалів при високих температурах. Деформування таких матеріалів при підвищенні температури описується за допомогою лінійної моделі механіки ...
Kucher, N., Ryzanov, R., Кучер, Николай Кирилович, Рязанов, Роман Александрович   +3 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

High temperature testing apparatus Patent [PDF]

, 1965
Test apparatus for determining mechanical properties of refractory materials at high temperatures in vacuum or inert ...
Sikora, P. F.
core   +1 more source