Results 81 to 90 of about 15,809,998 (339)
Advances in Materials Science and Engineering, 2023 Advances in Materials Science and Engineering
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
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Advances in Materials Science and Engineering, 2023 Advances in Materials Science and Engineering
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
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Advances in Materials Science and Engineering, 2023 Advances in Materials Science and Engineering
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
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Retracted: Tribological Behavior of AA7075 Reinforced with Ag and ZrO2 Composites
Advances in Materials Science and Engineering, 2023 Advances in Materials Science and Engineering
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Advances in Materials Science and Engineering, 2023 Advances in Materials Science and Engineering
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Advanced materials engineering in historical gypsum plaster formulations. [PDF]
Proc Natl Acad Sci U S A, 2023 Mishmastnehi M +4 more
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