Results 121 to 130 of about 1,402,582 (408)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Self-healing of microcapsule-based materials for highway construction: A review
Journal of Traffic and Transportation Engineering, 2023 Enlin Ma +4 more
semanticscholar +1 more source
Potential Utilization of Waste Material for Sustainable Development in construction Industry
International journal of recent technology and engineering, 2019 Billions of waste is produced in the world but the wastes are not properly recycled. Recycling of materials also different issues and it needs more energy.
semanticscholar +1 more source
Summary of tower designs for large horizontal axis wind turbines [PDF]
Towers for large horizontal axis wind turbines, machines with a rotor axis height above 30 meters and rated at more than 500 kW, have varied in configuration, materials of construction, type of construction, height, and stiffness.
Frederick, G. R., Savino, J. M.
core +1 more source
Mechanics of a Plant in Fluid Flow
, 2019 Plants live in constantly moving fluid, whether air or water. In response to the loads associated with fluid motion, plants bend and twist, often with great amplitude. These large deformations are not found in traditional engineering application and thus
Gosselin, Frederick P.
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Summary report: A preliminary investigation into the use of fuzzy logic for the control of redundant manipulators [PDF]
The Rice University Department of Mechanical Engineering and Materials Sciences' Robotics Group designed and built an eight degree of freedom redundant manipulator. Fuzzy logic was proposed as a control scheme for tasks not directly controlled by a human
Cheatham, John B., Jr., Magee, Kevin N.
core +1 more source
Undergraduate construction skills application [PDF]
, 2004 The case study is a "hands-on" simulation of construction site activities. Undertaken by 2nd year undergraduate students in construction courses at the Abertay University and involves building a full-scale reinforced concrete framed structure comprising ...
Ogwuda, Olisanwendu Ikechukwuka +2 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source