Results 91 to 100 of about 24,530,151 (408)

Laser-accelerated particle beams for stress testing of materials

Nature Communications, 2018
Laser-driven particle acceleration, obtained by irradiation of a solid target using an ultra-intense (I > 1018 W/cm2) short-pulse (duration
M. Barberio, M. Scisciò, M. Scisciò, S. Vallières, F. Cardelli, F. Cardelli, Sophia N Chen, G. Famulari, T. Gangolf, G. Revet, A. Schiavi, M. Senzacqua, P. Antici   +12 more
semanticscholar   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

Bond line shear strength of structural wood adhesives at high temperatures up to wood carbonization – A classification approach

Results in Engineering
The European timber fire design code EN 1995-1-2 presently specifies that adhesives for timber construction products shall provide integrity throughout the intended fire exposure time, yet no test or requirement specifications are given.
Simon Aicher, Maximilian Henning, Aaron Münzer   +2 more
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Hulk Smash”™ Busting the OAA Silo! [PDF]

, 2015
This poster focuses on Lavery Library’s collaboration with the Office of Academic Affairs, OAA. At St. John Fisher College students with learning disabilities testing accommodations take their exams in the library instead of a testing center.
Celata, Stacy
core   +1 more source

Feasibility Study on Laser Powder Bed Fusion of Ferritic Steel in High Vacuum Atmosphere

Journal of Manufacturing and Materials Processing
The boiling point of metals is dependent on the ambient pressure. Therefore, in laser-based fusion welding and additive manufacturing processes, the resulting process regime, ranging from heat conduction welding to the keyhole mode, is also influenced by
Steffen Fritz, Sven Sewalski, Stefan Weihe, Martin Werz   +3 more
doaj   +1 more source

Impact of the Process Parameters, the Measurement Conditions and the Pre-Machining on the Residual Stress State of Deep Rolled Specimens

Journal of Manufacturing and Materials Processing, 2019
Mechanical surface treatments, e.g., deep rolling, are widely spread finishing processes due to their ability to enhance the fatigue strength of the treated materials with means of cold working and inducement of favorable compressive residual stresses ...
Nataliya Lyubenova, Dirk Bähre, Lukas Krupp, Julie Fouquet, Titouan Cronier, Jay Patel, Joachim Ernst Hoffmann   +6 more
doaj   +1 more source

Growing and testing mycelium bricks as building insulation materials

, 2018
In order to improve energy performance of buildings, insulation materials (such as mineral glass and rock wools, or fossil fuel-based plastic foams) are being used in increasing quantities, which may lead to potential problem with materials depletions ...
Yang Xing, M. Brewer, H. El-Gharabawy, G. Griffith, P. Jones   +4 more
semanticscholar   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Testing of typical spacecraft materials in a simulated substorm environment [PDF]

, 1977
The test specimens were spacecraft paints, silvered Teflon, thermal blankets, and solar array segments. The samples, ranging in size from 300 to 1000 sq cm were exposed to monoenergetic electron energies from 2 to 20 keV at a current density of 1 NA/sq ...
Berkopec, F. D., Blech, R. A., Narciso, S. J., Staskus, J. V., Stevens, N. J.   +4 more
core   +1 more source