Results 71 to 80 of about 8,899,666 (297)
Repetitive Availability Demonstration Testing Procedure
The proposed availability demonstration test (ADT) is an extension of the work of Usher and Taylor [Usher, J.S. and Taylor, G.D., "Availability Demonstration Testing," Qual. Reliab. Eng. Int., Vol. 22, No. 4, 2006, pp.
Usher, J. S. +3 more
core +1 more source
Mechanical surface treatments, e.g., deep rolling, are widely spread finishing processes due to their ability to enhance the fatigue strength of the treated materials with means of cold working and inducement of favorable compressive residual stresses ...
Nataliya Lyubenova +6 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An electrically and mechanically sound joint between aluminum and copper is essential in modern manufacturing, particularly in the field of e-mobility, where the demand for integrated, lightweight, and high-performance conductors continues to grow ...
Lucia Sauter, Martin Werz, Stefan Weihe
doaj +1 more source
Online immunocapture ICP-MS for the determination of the metalloprotein ceruloplasmin in human serum
Objective The human copper-protein ceruloplasmin (Cp) is the major copper-containing protein in the human body. The accurate determination of Cp is mandatory for the reliable diagnosis of several diseases.
Bogdan Bernevic +3 more
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

