Results 61 to 70 of about 4,042,136 (301)

Determination of the effects of the rebar-cement bond parameters variation in UHPFRC using FA and ANN [PDF]

Science of Sintering
The experimental study included the design and production of ultra-high performance steel fiber-reinforced concrete (UHPFRC). The physical and mechanical properties of UHPFRC were investigated in a laboratory setting.
Bojović Dragan, Terzić Anja, Nikolić Dragan, Janković Ksenija   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Corundum Particles as Trypsin Carrier for Efficient Protein Digestion

BioTech
Reusable enzyme carriers are valuable for proteomic workflows, yet many supports are expensive or lack robustness. This study describes the covalent immobilization of recombinant trypsin on micrometer-sized corundum particles and assesses their ...
Sarah Döring, Birte S. Wulfes, Aleksandra Atanasova, Carsten Jaeger, Leopold Walzel, Georg Tscheuschner, Sabine Flemig, Kornelia Gawlitza, Ines Feldmann, Zoltán Konthur, Michael G. Weller   +10 more
doaj   +1 more source

Very High Cycle Fatigue Behavior of TA11 Titanium Alloy

Journal of Aeronautical Materials, 2017
The conventional fatigue test method was used to obtain the very high cycle fatigue (VHCF) limits of 3×107 and 1×108 cycles for TA11 titanium alloy in different temperatures and stress ratios.
JIAO Zehui, YU Huichen, ZHONG Bin, LI Xudong, ZHOU Jingyi   +4 more
doaj   +1 more source

Fracture toughness testing data: A technology survey and bibliography [PDF]

, 1975
Announced survey includes reports covering fracture toughness testing for various structural materials including information on plane strain and developing areas of mixed mode and plane strain test conditions.
Carpenter, J. L., Jr., Mandel, G., Moya, N., Stuhrke, W. F.   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Squaraine Planar-Heterojunction Solar Cells

International Journal of Photoenergy, 2009
The photovoltaic performance of squaraine-based organic solar cells is investigated. Two squaraine derivatives with extraordinarily high extinction coefficients are used as electron donors in bilayer heterojunctions with fullerene C60 as electron ...
Bin Fan, Ylenia Maniglio, Marina Simeunovic, Simon Kuster, Thomas Geiger, Roland Hany, Frank Nüesch   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Embedding and cross-sectioning as a sample preparation procedure for accurate and representative size and shape measurement of nanopowders

Scientific Reports
Reliable measurement of the size of polydisperse, complex-shaped commercial nanopowders is a difficult but necessary task, e.g., for regulatory requirements and toxicity risk assessment.
Paul Mrkwitschka, Bastian Rühle, Petra Kuchenbecker, Oliver Löhmann, Franziska Lindemann, Vasile-Dan Hodoroaba   +5 more
doaj   +1 more source