Results 61 to 70 of about 1,805,079 (341)
The testing of insulating materials
Materials & Design, 1989 Abstract ERA Technology has devised a set of standardised tests which can be used to assess the performance of materials for different aspects of electrical low voltage switching applications. Different moulding materials were studied in conjunction with one contact materials, with the primary objective of investigating the effect of the moulding ...
D Charman, RA Simmonds
openaire +2 more sources
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Electron irradiation: from test to material tailoring [PDF]
arXiv, 2023 In this article, we report some examples of how high-energy electron irradiation can be used as a tool for shaping material properties turning the generation of point-defects into an advantage beyond the presumed degradation of the properties. Such an approach is radically different from what often occurs when irradiation is used as a test for ...
arxiv
Design and testing of 3D-printed micro-architectured polymer materials exhibiting a negative Poisson's ratio [PDF]
Continuum Mech. Thermodyn. 32, 433-449 (2020), 2018 This work proposes the complete design cycle for several auxetic materials where the cycle consists of three steps (i) the design of the micro-architecture, (ii) the manufacturing of the material and (iii) the testing of the material. We use topology optimization via a level-set method and asymptotic homogenization to obtain periodic micro ...
arxiv +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Validation of the material point method and plasticity with Taylor impact tests [PDF]
arXiv, 2012 Taylor impacts tests were originally devised to determine the dynamic yield strength of materials at moderate strain rates. More recently, such tests have been used extensively to validate numerical codes for the simulation of plastic deformation. In this work, we use the material point method to simulate a number of Taylor impact tests to compare ...
arxiv
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source