Results 61 to 70 of about 2,406,442 (245)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Squaraine Planar-Heterojunction Solar Cells

open access: yesInternational Journal of Photoenergy, 2009
The photovoltaic performance of squaraine-based organic solar cells is investigated. Two squaraine derivatives with extraordinarily high extinction coefficients are used as electron donors in bilayer heterojunctions with fullerene C60 as electron ...
Bin Fan   +6 more
doaj   +1 more source

Friction and Wear Behaviour of Graphite Filled Polymer Composites in Hydrogen Environment

open access: yesTribology Online, 2015
High performance polymer composites have been intensively investigated for tribological applications in air, but rarely in hydrogen environment. Author’s previous benchmark of composites in liquid hydrogen (LH2) showed that graphite filled polymers have ...
Géraldine Theiler, Thomas Gradt
doaj   +1 more source

An Ultra-High Frequency Vibration-Based Fatigue Test and Its Comparative Study of a Titanium Alloy in the VHCF Regime

open access: yesMetals, 2020
This paper proposes an ultra-high frequency (UHF) fatigue test of a titanium alloy TA11 based on electrodynamic shaker in order to develop a feasible testing method in the VHCF regime.
Wei Xu   +6 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Bond line shear strength of structural wood adhesives at high temperatures up to wood carbonization – A classification approach

open access: yesResults in Engineering
The European timber fire design code EN 1995-1-2 presently specifies that adhesives for timber construction products shall provide integrity throughout the intended fire exposure time, yet no test or requirement specifications are given.
Simon Aicher   +2 more
doaj   +1 more source

Hulk Smash”™ Busting the OAA Silo! [PDF]

open access: yes, 2015
This poster focuses on Lavery Library’s collaboration with the Office of Academic Affairs, OAA. At St. John Fisher College students with learning disabilities testing accommodations take their exams in the library instead of a testing center.
Celata, Stacy
core   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Feasibility Study on Laser Powder Bed Fusion of Ferritic Steel in High Vacuum Atmosphere

open access: yesJournal of Manufacturing and Materials Processing
The boiling point of metals is dependent on the ambient pressure. Therefore, in laser-based fusion welding and additive manufacturing processes, the resulting process regime, ranging from heat conduction welding to the keyhole mode, is also influenced by
Steffen Fritz   +3 more
doaj   +1 more source

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