Results 81 to 90 of about 1,642,260 (307)

Face Masks in the New COVID-19 Normal: Materials, Testing, and Perspectives. [PDF]

open access: yesResearch (Wash D C), 2020
Chua MH   +16 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Local lattice distortions and chemical short-range order in MoNbTaW

open access: yesMaterials Research Letters
Extended X-ray absorption fine structure (EXAFS) conducted on an equiatomic MoNbTaW bcc medium-entropy alloy that was annealed at 2273 K reveals unexpectedly small 1st and 2nd shell element-specific lattice distortions.
Andrea Fantin   +4 more
doaj   +1 more source

Materials Testing for the Development of Biocompatible Devices through Vat-Polymerization 3D Printing. [PDF]

open access: yesNanomaterials (Basel), 2020
González G   +7 more
europepmc   +1 more source

Rasch modeling: Developing a critical thinking ability test for students on climate change material

open access: gold, 2023
Irwan Muhammad Ridwan   +5 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Effect of tool material on joint quality in friction stir welding of aluminum-steel tailor welded blanks

open access: yesJournal of Advanced Joining Processes
Friction stir welding (FSW) enables high-strength joints between dissimilar materials such as aluminum and steel and is particularly suited for hybrid tailor welded blanks in deep drawing.
Robin Göbel   +3 more
doaj   +1 more source

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