Results 221 to 230 of about 250,542 (292)

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

A New Hyaluronic Emulgel of Hesperetin for Topical Application-An In Vitro Evaluation. [PDF]

J Funct Biomater
Taléns-Visconti R, Belarbi Y, Díez-Sales O, Julián-Ortiz JV, Vila-Busó O, Nácher A.   +5 more
europepmc   +1 more source

Matières premières/materias primas

, 2021
openaire   +2 more sources

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

Efecto económico parcial de la covid-19 y sus resultados en Camagüey, Cuba

, 2020
González Torres IM, Collado Cardoso E, Torres Mora IJ, Quiroga Gómez ZM, Morán Giraldo C, Gomez Rosabal A.   +5 more
europepmc   +1 more source

Synthesis of NdAlO₃ Nanoparticles and Evaluation of the Catalytic Capacity for Biodiesel Synthesis. [PDF]

Nanomaterials (Basel), 2019
Dionicio-Navarrete M, Arrieta-Gonzalez CD, Quinto-Hernandez A, Casales-Diaz M, Zuñiga-Diaz J, Porcayo-Calderon J, Martinez-Gomez L.   +6 more
europepmc   +1 more source

Żywioły wyobraźni : woda - "materia prima"

, 2017
The introduction to the fi rst of four collective monographs on elements in children’s literature describes synthetically the signifi cance of four elements in the European tradition, including brief explanation of water symbolic meanings and emphasizing their importance in culture.
openaire   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, Volume 13, Issue 14, 9 March 2026.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding, Zhongxiong Fan, Guoyu Xia, Fukai Zhu, Nan Yang, Shujie Yu, Longlong Yuan, Jinyao Li   +7 more
wiley   +1 more source