Results 131 to 140 of about 30,242 (281)

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell   +3 more
wiley   +1 more source

Neonatal hyperbilirubinemia due to ABO incompatibility: does blood group matter?

open access: yesThe Turkish Journal of Pediatrics, 2013
Newborn infants with maternal-fetal ABO incompatibility are at a greater risk for developing subsequent significant hyperbilirubinemia, and therefore, prediction of probable risk factors, such as the degree of hemolysis, gains importance.
Sinem Akgül   +3 more
doaj  

MCT1‐mediated bidirectional propionate transport across human placental syncytiotrophoblast layer: insights from a trophoblast stem cell‐derived barrier model

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Propionate in the fetal circulation is thought to originate from fermentation of dietary fibre by the maternal gut microbiota. However, the mechanism of transplacental transport has remained unclear. Here, we measured propionate permeability using a placental barrier model generated by differentiating human placental trophoblast ...
Toshiaki Tsuchitani   +8 more
wiley   +1 more source

Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development. [PDF]

open access: yesCompr Physiol
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Xu S   +6 more
europepmc   +2 more sources

Physiological and anatomical determinants of placental drug transfer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis   +3 more
wiley   +1 more source

THE EFFECTS OF MATERNAL HYPEROXIA ON FETAL BREATHING MOVEMENTS, BODY MOVEMENTS AND HEART-RATE VARIATION IN GROWTH RETARDED FETUSES

open access: yes, 1991
In hypoxemic intrauterine growth-retarded fetuses (IUGR) there is a reduction in the incidence of fetal movements and in fetal heart rate variation. A causal relationship with the impairment of fetal oxygenation has been suggested. In 16 IUGR fetuses and
VISSER, GHA   +3 more
core   +1 more source

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida   +7 more
wiley   +1 more source

Ammonia Levels in Maternal and Fetal Tissues and Blood of Urea-Treated Sheep

open access: yes, 1974
Ammonia toxicosis is known to be a problem of nonprotein nitrogen or urea feeding in ruminant animals. Urea is hydrolyzed in the gastrointestinal tract in the presence of bacterial urease to ammonia and carbon dioxide.
Yelverton, Charles C.
core  

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass   +2 more
wiley   +1 more source

An evaluation of self esteem, social support and maternal-fetal attachment in the pregnant adolescent

open access: yes, 1991
The purpose of this descriptive correlational study was to evaluate any association between self esteem, maternal-fetal attachment and social support of the pregnant adolescent.
Eisenhower, Olga Chesteen
core  

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