Results 91 to 100 of about 6,033,440 (255)
Student's Journal of Health Research AfricaBackground: Gestational Diabetes Mellitus (GDM) is a growing public health concern with significant implications for both maternal and fetal health. Identifying its prevalence and associated risk factors is essential for timely diagnosis and preventive ...
Dr. soujanya Bukke, M.S (OBG) +2 more
doaj +1 more source
Advanced Science, EarlyView.Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo +10 more
wiley +1 more source
Advanced Science, EarlyView.An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee +11 more
wiley +1 more source
Frontiers in EndocrinologyPurposeThis study aimed to determine whether embryonic aneuploidy rates differ between patients with and without recurrent pregnancy loss (RPL).MethodsThis retrospective cohort study included 103 patients with RPL undergoing 128 preimplantation genetic ...
Sui-Bing Miao +5 more
doaj +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Frontiers in PediatricsObjectiveThis study aims to systematically evaluate the primary influencing factors of birth defects in China from 2019 to 2025, providing evidence for decision-making and intervention measures in the prevention of birth defects.MethodsA comprehensive ...
Min Yang +7 more
doaj +1 more source
Age-period-cohort model trend analysis of maternal mortality.
, 2020 Age-period-cohort model trend analysis of maternal mortality.
Tippawan Liabsuetrakul (6646876) +3 more
core +1 more source
Advanced Science, EarlyView.NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu +10 more
wiley +1 more source
Acta Obstetricia et Gynecologica ScandinavicaIntroduction In this register‐based study of pregnancies in Denmark, we assessed the associations between maternal age and the risk of fetal aneuploidies (trisomy 21, trisomy 18, trisomy 13, triploidy, monosomy X and other sex chromosome aberrations ...
Line Elmerdahl Frederiksen +8 more
doaj +1 more source
Frontiers in Public HealthBackgroundEarly pregnancy is associated with increased psychosocial vulnerability, which has been linked to factors associated with child maltreatment. However, previous research has predominantly focused on teenagers, and little is known about whether ...
Kaori Baba +19 more
doaj +1 more source