Results 81 to 90 of about 6,033,440 (255)

Maternal Mortality in Klaten Regency (Determinant Factors Analysis)

open access: yes, 2021
Background: Failure in reducing maternal mor­­­­­­tality has become one of the world's health prob­­­lems. Indonesia ranks third on the list of the highest MMR in ASEAN countries.
Sesunan, Arfan Syahfani   +2 more
core  

Maternal response to environmental unpredictability [PDF]

open access: yes, 2015
This study was funded by a postdoctoral fellowship to MB (SFRH/BPD/82259/2011) and with a “Bolsista CAPES/BRASIL,” (Project A058/2013) to AMVMS.Mothers are expected to use environmental cues to modify maternal investment to optimize their fitness ...
Lopes, Isabel   +14 more
core   +1 more source

SDF‐1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy‐Enhanced Stress Granule Scavenging

open access: yesAdvanced Science, EarlyView.
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long   +12 more
wiley   +1 more source

Association between maternal age and postpartum depression in Ardabil, Northwest of Iran: a cross-sectional study [PDF]

open access: yesPatient Safety and Quality Improvement Journal
Introduction: Postpartum depression (PPD) is a mood disorder that negatively affects mother, child and family. This study aims to examine the association between maternal age and postpartum depression.
Afrouz Mardi   +4 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

Paternal age and the risk of cerebral palsy

open access: yesAnthropological Review, 2020
In the literature there are no unequivocal assessments of the effect of paternal age on the risk of cerebral palsy (CP). The objective of the studies was the analysis of the influence of paternal age on this risk, considering all the important risk ...
Sternal Marta   +3 more
doaj   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

open access: yesAdvanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao   +5 more
wiley   +1 more source

Risk Factors of Maternal Death in Karanganyar, Central Java, Indonesia [PDF]

open access: yes, 2019
Background: The maternal mortality rate is an indicator of national health status. To reduce the Maternal Mortality Rate (MMR), especially in Karanganyar Regency, the risk factors that affect maternal mortality must be known.Subjects and Method:  This ...
Kusnadi, Noferi   +2 more
core  

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

open access: yesAdvanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae   +5 more
wiley   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

open access: yesAdvanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang   +18 more
wiley   +1 more source

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