Results 111 to 120 of about 5,793,459 (255)

Maternal smoking and congenital malformations

, 2002
Since the first report by Simpson (1957) of the association between premature birth and maternal smoking, the research on the consequences of maternal smoking during pregnancy on perinatal outcome has been intense.
Källén, Karin,, Lund University.
core   +2 more sources

Maternal, healthcare, and nutritional factors influencing birth defects in China from 2019 to 2025: a systematic review and meta-analysis

Frontiers in Pediatrics
ObjectiveThis study aims to systematically evaluate the primary influencing factors of birth defects in China from 2019 to 2025, providing evidence for decision-making and intervention measures in the prevention of birth defects.MethodsA comprehensive ...
Min Yang, Min Yang, Jia Lv, Tianzhi Guo, Min Ren, Lingling Xie, Suhua Tu, Suhua Tu   +7 more
doaj   +1 more source

LncRNA FLJ20021 Restrains Fibroblast Senescence and Matrix Remodeling in Pelvic Organ Prolapse by Promoting XRCC6‐Dependent ADI1 Transcription

Advanced Science, EarlyView.
FLJ20021 interacts with XRCC6 to regulate ADI1 transcription and downstream cellular phenotypes in hUSLFs. Reduced FLJ20021 in POP is associated with lower ADI1, increased apoptosis, senescence, and an ECM‐degrading marker profile. Conversely, FLJ20021 overexpression enhances XRCC6‐dependent ADI1 expression, reduces apoptosis and senescence, and shifts
YanFeng Yang, BingJie Rui, GuangHai Rui, YiNan Duan, Ji Hyang Kim   +4 more
wiley   +1 more source

Maternal age and the risk of fetal aneuploidy: A nationwide cohort study of more than 500 000 singleton pregnancies in Denmark from 2008 to 2017

Acta Obstetricia et Gynecologica Scandinavica
Introduction In this register‐based study of pregnancies in Denmark, we assessed the associations between maternal age and the risk of fetal aneuploidies (trisomy 21, trisomy 18, trisomy 13, triploidy, monosomy X and other sex chromosome aberrations ...
Line Elmerdahl Frederiksen, Sofie Møller Ølgaard, Laura Roos, Olav Bjørn Petersen, Line Rode, Tanja Hartwig, Charlotte Kvist Ekelund, the Danish Central Cytogenetics Registry Study Group, Ida Vogel   +8 more
doaj   +1 more source

PREVALENCE AND RISK FACTORS OF GESTATIONAL DIABETES MELLITUS (GDM) IN PREGNANT WOMEN: A CROSS-SECTIONAL STUDY.

Student's Journal of Health Research Africa
Background: Gestational Diabetes Mellitus (GDM) is a growing public health concern with significant implications for both maternal and fetal health. Identifying its prevalence and associated risk factors is essential for timely diagnosis and preventive ...
Dr. soujanya Bukke, M.S (OBG) , Anisa Begum , Poojitha Dubbudu   +2 more
doaj   +1 more source

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source

Timing of assisted hatching and blastocyst euploidy: A prospective PGT-A study

Asian Pacific Journal of Reproduction
Objective: To investigate whether the timing of assisted hatching (AH) independently influences blastocyst euploidy after adjustment for maternal age and blastocyst morphology.
Hoang Minh Ngan, Tran Thi Thuy, Tran Quang Anh, Nguyen Dinh Tao, Vu Thi Hanh   +4 more
doaj   +1 more source

The Relationship between Maternal Characteristics and Health Workers Role on Early Complementary Feeding in the Era of the COVID-19 Pandemic

, 2021
Background: Early complementary feeding in Indonesia, especially in Palu city, is still relatively high and should focus. Early complementary feeding can negatively affect babies, such as being more susceptible to disease than babies who only get breast ...
Ramadhani, Fitri, Frety, Endyka Erye, Husada, Dominicus   +2 more
core  

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

Maternal autonomy and the education of the subsequent generation : evidence from three contrasting states in India [PDF]

, 2011
This paper makes a significant contribution on both conceptual and methodological fronts, in the analysis of the effect of maternal autonomy on school enrolment age of children in India.
Alfano, Marco, Kambhampati, Uma, Arulampalam, Wiji, Kambhampati, Uma S.   +3 more
core