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Maternal Age and Infant Health
We study the effects of maternal age on infant health. Age at birth has been increasing for the past several decades in many countries, and correlations show that health at birth is worse for children born to older mothers. In order to identify causal effects, we exploit school entry cutoffs and the empirical finding that women who are older for their ...
Borra, Cristina+2 more
openaire +5 more sources
The average age of women at childbirth in industrialised nations has been increasing steadily for approximately 30 years. Women aged 35 years or over have an increased risk of gestational hypertensive disease, gestational diabetes, placenta praevia, placental abruption, perinatal death, preterm labour, fetal macrosomia and fetal growth restriction ...
Kate F. Walker, Jim G Thornton
openaire +2 more sources
Maternal Age and Child Development [PDF]
Abstract Although the consequences of teen births for both mothers and children have been studied for decades, few studies have taken a broader look at the potential payoffs—and drawbacks—of being born to older mothers. A broader examination is important given the growing gap in maternal ages at birth for children born to mothers with ...
Duncan, Greg J+3 more
openaire +4 more sources
ObjectiveTo explore the cumulative outcomes and influencing factors of patients with discrepancies between age and Anti-Müllerian hormone (AMH) levels in the early follicular phase prolonged protocol.MethodsA total of 1282 cycles of in-vitro ...
Kexin Wang+7 more
doaj +1 more source
Cohesin and the Maternal Age Effect [PDF]
During meiosis in human oocytes, chromosome nondisjunction increases with maternal age, leading to disorders such as Down's syndrome. In a recent study in Nature Genetics, Hodges et al. (2005) show that mice with a mutation in the meiosis-specific cohesin protein SMC1beta exhibit age-dependent defects in meiosis.
R. Scott Hawley, William D. Gilliland
openaire +3 more sources
Trends in epidemiology of hyperglycemia in pregnancy in Taiwan, 2008-2017
BackgroundHyperglycemia in pregnancy (HIP) increases the risk of adverse pregnancy outcomes. The increasing prevalence of overweight or obesity and the increasing proportion of pregnant women with advanced maternal age (AMA) in the recent decade may ...
Shin-Yu Lin+11 more
doaj +1 more source
NLRP2 controls age-associated maternal fertility [PDF]
Nucleotide-binding domain and leucine-rich repeat (NLR) proteins are well-known for their key roles in the immune system. Ectopically expressed NLRP2 in immortalized cell lines assembles an inflammasome and inhibits activation of the proinflammatory ...
Agostini+24 more
core +2 more sources
Older pregnant women have increased risks of complications including gestational diabetes and stillbirth. Carnitine palmitoyl transferase (CPT) expression declines with age in several tissues and is linked with poorer metabolic health. Mitochondrial CPTs
Hannah E. J. Yong+19 more
doaj +1 more source
Maternal corticotropin-releasing hormone is associated with LEP DNA methylation at birth and in childhood: an epigenome-wide study in Project Viva [PDF]
BackgroundCorticotropin-releasing hormone (CRH) plays a central role in regulating the secretion of cortisol which controls a wide range of biological processes. Fetuses overexposed to cortisol have increased risks of disease in later life.
A Cardenas+72 more
core +1 more source
Maternal risk factors associated with term low birth weight in India: A review
Low birth weight is one of the leading factors for infant morbidity and mortality. To a large extent affect, various maternal risk factors are associated with pregnancy outcomes by increasing odds of delivering an infant with low birth weight.
Harsh Vats+4 more
doaj +1 more source