Results 41 to 50 of about 6,033,440 (255)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Exploration of the Clinico-Biochemical Parameters to Explain the Altered Renal Mechanisms in Gestational Diabetes Mellitus [PDF]

Journal of Clinical and Diagnostic Research, 2012
Context: Gestational diabetes mellitus (GDM) is a common metabolic abnormality which affects ~2-5% of the pregnancies annually. Various risk factors such as advanced maternal age, previous infants with macrosomia, a strong family history of non ...
Nagalakshmi C.S., Devaki R.N., Akila P, Suma K.B., Prashant V., Suma M.N., Parveen D., Sujatha P.   +7 more
doaj  

The association of maternal prenatal psychosocial stress with vascular function in the child at age 10-11 years: findings from the Avon longitudinal study of parents and children [PDF]

, 2014
Objective To investigate whether (1) maternal psychosocial stress (depression/anxiety) during pregnancy is associated with offspring vascular function and (2) whether any association differs depending on the gestational timing of exposure to stress.
Gemke, Reinoud J. B. J., Stronks, K, Vrijkotte, T., Gemke, R., Dawe, Karen, Vrijkotte, Tanja G. M., Stronks, Karien, Deanfield, John, Dawe, K., van Dijk, AE, Dawe, K, Gemke, RJ, Lawlor, D., Lawlor, Debbie A., Van Dijk, A., Deanfield, J, Vrijkotte, TG, Lawlor, DA, van Dijk, Aimée E., Deanfield, J., Gemke, R.J.B.J., Stronks, K., Vrijkotte, T.G.M., Van Dijk, A.E., Lawlor, D.A.   +24 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

The level and duration of RSV-specific maternal IgG in infants in Kilifi Kenya [PDF]

, 2009
Background Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in infants. The rate of decay of RSV-specific maternal antibodies (RSV-matAb), the factors affecting cord blood levels, and the relationship between ...
Nokes D. James, Ochola Rachel, Cane Patricia A., Scott, P. D. (Paul D.), Charles Sande, Medley Graham F., Fegan, Gregory, Scott, Paul D, Rachel Ochola, Greg Fegan, Cane, Patricia, Scott Paul D., Cane, Patricia A, Nokes, D. James, Paul D Scott, Sande Charles, Sande, Charles, Fegan Gregory, Medley, Graham F, Patricia A Cane, Fegan, Greg, D James Nokes, Ochola, Rachel, Medley, Graham, Graham F Medley, Nokes, D James, Gregory Fegan   +26 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Effects of Maternal Age on Fetus and Perinatal Outcomes in a Tertiary Care Center: An Observational Study

Journal of Nepal Medical Association
Introduction: The early and late pregnancy both can be hazardous for mother and child. The study aims to explore the maternal age group among Nepalese women who delivered in Tribhuvan University Teaching Hospital and its effects on perinatal outcomes ...
Sonam Chaudhary, Narayan Mahotra, Pooja Paudyal   +2 more
doaj   +1 more source

Maternal age and endogenous variation in maternal influence on photoperiodic response in the progeny diapause in Trichogramma embryophagum (Hymenoptera: Trichogrammatidae)

European Journal of Entomology, 2002
A laboratory study was carried out on photoperiodic control of prepupal diapause in the egg parasitoid Trichogramma embryophagum (Hartig). All experiments were conducted with an isofemale parthenogenetic strain. The maternal generation was reared at 20°C
Sergey Ya. REZNIK, Tatyana S. KATS, Taisiya Ya. UMAROVA, Nataliya D. VOINOVICH   +3 more
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source