Results 31 to 40 of about 538,059 (267)

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

Impact of the COVID-19 Pandemic on Pediatric Neuropsychiatric Disorders: A Retrospective Study at a Single Center for Child Neurology and Psychiatry

Children
Background: The COVID-19 pandemic and related containment measures profoundly affected child and adolescent mental health, with increasing evidence of a rise in psychiatric symptomatology and healthcare burden.
Giulia Spoto, Cecilia Spoto, Liliana Ruta, Gennaro Tartarisco, Roberta Bruschetta, Natalia Carolina Arminio, Caterina Sferro, Maria Spanò, Marilena Briguglio, Anna Cafeo, Greta Amore, Ambra Butera, Arianna Mancini, Arianna Currò, Maria Pia Lizio, Maria Ludovica Albertini, Carla Consoli, Graziana Ceraolo, Antonio Gennaro Nicotera, Gabriella Di Rosa   +19 more
doaj   +1 more source

A Comparative Study on Adverse Pregnancy Outcomes in Pregnant Women with Different Age

Journal of Holistic Nursing and Midwifery, 2021
Introduction: Delayed childbearing is increasing. Increased maternal age has been associated with increased risk of pregnancy complications. On the other hand, the adolescent pregnancy has traditionally been considered high-risk, especially in developing
Soudabe Ebrahimi, Maryam Niknami, Fateme Rafat, Ehsan Kazemnezhad Leili   +3 more
doaj  

Maternal age at birth and daughter’s fecundability

Human Reproduction, 2021
AbstractSTUDY QUESTIONDo daughters of older mothers have lower fecundability?SUMMARY ANSWERIn this cohort study of North American pregnancy planners, there was virtually no association between maternal age ≥35 years and daughters’ fecundability.WHAT IS KNOWN ALREADYDespite suggestive evidence that daughters of older mothers may have lower fertility ...
Basso, Olga, Willis, Sydney K., Hatch, Elizabeth E., Mikkelsen, Ellen M., Rothman, Kenneth J., Wise, Lauren A.   +5 more
openaire   +3 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Efficacy and safety of cannabidiol in a single-center pediatric drug-resistant epilepsy cohort: a retrospective study

Frontiers in Neurology
BackgroundPharmacoresistance to conventional antiseizure medications has been described in approximately 30% of the pediatric epileptic patients, making pharmacological management particularly challenging for physicians.
Ambra Butera, Ambra Butera, Giulia Spoto, Graziana Ceraolo, Maria Grella, Ivana Giunta, Maria Ludovica Albertini, Carla Consoli, Caterina Sferro, Maria Spanò, Gabriella Di Rosa, Antonio Gennaro Nicotera   +11 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

First-trimester ultrasound diagnosis of sirenomelia: A case report

Case Reports in Women's Health
Sirenomelia is a rare congenital malformation characterized by the fusion of the lower limbs and is generally associated with severe multisystem anomalies.
Carla Ettore, Elisa Pappalardo, Ferdinando Antonio Gulino, Giosuè Giordano Incognito, Sebastiano Bianca, Giuseppe Ettore   +5 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Exploration of the Clinico-Biochemical Parameters to Explain the Altered Renal Mechanisms in Gestational Diabetes Mellitus [PDF]

Journal of Clinical and Diagnostic Research, 2012
Context: Gestational diabetes mellitus (GDM) is a common metabolic abnormality which affects ~2-5% of the pregnancies annually. Various risk factors such as advanced maternal age, previous infants with macrosomia, a strong family history of non ...
Nagalakshmi C.S., Devaki R.N., Akila P, Suma K.B., Prashant V., Suma M.N., Parveen D., Sujatha P.   +7 more
doaj