Families' social backgrounds matter : socio-economic factors, home learning and young children's language, literacy and social outcomes [PDF]
, 2011 Parental support with children's learning is considered to be one pathway through which socio-economic factors influence child competencies. Utilising a national longitudinal sample from the Millennium Cohort Study, this study examined the relationship ...
Aber J. L. +24 more
core +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
5-HT2A Receptors Modulate Dopamine D2-mediated Maternal Effects [PDF]
, 2020 Serotonin 5-HT2A receptors are expressed throughout the mesolimbic and mesocortical dopamine pathways, and manipulation of this receptor system has a profound impact on dopamine functions and dopamine-mediated behaviors.
Gao, Jun
core +1 more source
A study to assess the effect of maternal hemoglobin level on foetal outcome among antenatal mothers in selected maternity hospitals at Mangalore [PDF]
, 2023 SONIA SEBASTIAN
openalex +1 more source
Advanced Science, EarlyView.This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen +8 more
wiley +1 more source
Genetic parameters for direct and maternal genetic components of calving ease in Korean Holstein Cattle using animal models [PDF]
Animal BioscienceObjective We investigated genetic parameters of calving ease (CE) using several animal models in Korean Holstein and searched for suitable models for routine evaluation of CE.
Mahboob Alam +11 more
doaj +1 more source
Effect of Maternal Practices Educational Program on Quality of Life for Their Epileptic Children [PDF]
, 2023 Hanaa Mohamed +3 more
openalex +1 more source
Advanced Science, EarlyView.This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou +7 more
wiley +1 more source
Genetic correlation analysis of calving ease and gestation length of Korean Holstein cattle [PDF]
Animal BioscienceObjective To investigate genetic correlation between calving ease (CE) and gestation length (GL) traits of Korean Holstein cattle to understand genetic structures of these two traits and their potential implications.
Mahboob Alam +11 more
doaj +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source