Results 141 to 150 of about 1,033,771 (354)

Direct additive genetics and maternal effect contribute to the risk of Tourette disorder. [PDF]

open access: yesJ Neurol Neurosurg Psychiatry, 2023
Mahjani B   +8 more
europepmc   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

open access: yesAdvanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu   +11 more
wiley   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li   +10 more
wiley   +1 more source

A more accurate analysis of maternal effect genes by siRNA electroporation into mouse oocytes. [PDF]

open access: yesJ Reprod Dev, 2023
Yamamoto T   +5 more
europepmc   +1 more source

The effect of nursing education strategies based on health promotion model on increasing family independence in caring for maternal health [PDF]

open access: hybrid, 2022
Naharia Laubo   +9 more
openalex   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

open access: yesAdvanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia   +4 more
wiley   +1 more source

Mitochondrial DNA content in eggs as a maternal effect. [PDF]

open access: yesProc Biol Sci, 2022
Kim SY   +3 more
europepmc   +1 more source

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