Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae +5 more
wiley +1 more source
Background: Immunization is a process that makes a person immune or immune to infectious diseases, usually by administering vaccines. A child is said to have received complete basic immunization if he has received one BCG immunization, three DPT-HB-Hib
Widyaningsih, Vitri +2 more
core
m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang +18 more
wiley +1 more source
Effect of Family Hope Program on Maternal Health Behavior and Children Under Five Nutritional Status in Poor Families, Jombang, East Java [PDF]
Background: Family Hope Program, or internationally referred to as Conditional Cash Transfer (CCT), is a government poverty allevation initiative by provision of conditional cash money that induces healthy behavior so as to achieve strong generation ...
Rosalina, Sintya +2 more
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Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo +10 more
wiley +1 more source
The Association between Exclusive Breastfeeding, Maternal Nutritional Status, Maternal Zinc Intake, and Stunting in Infants Aged 6 Months [PDF]
Background: Stunting is a form of malnutrition that has an impact on decreased learning achievement, motor and mental development and intellectual.
Salimo, Harsono +2 more
core
BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li +8 more
wiley +1 more source
A flying start? Long term consequences of maternal time investments in children during their first year of life [PDF]
We study the impact of increasing the time that the mother spends with her child in the first year of her life. In particular, we examine a reform that increased paid and unpaid maternity leave entitlements in Norway. In response to this reform, maternal
Kjell G. Salvanes +2 more
core
Risk Factors of Maternal Death in Karanganyar, Central Java, Indonesia [PDF]
Background: The maternal mortality rate is an indicator of national health status. To reduce the Maternal Mortality Rate (MMR), especially in Karanganyar Regency, the risk factors that affect maternal mortality must be known.Subjects and Method: This ...
Kusnadi, Noferi +2 more
core
NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou +6 more
wiley +1 more source

