Results 91 to 100 of about 9,771,033 (210)

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

open access: yesAdvanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi   +9 more
wiley   +1 more source

Maternal Provisioning of Offspring With Defence Chemicals in a Facultatively Parthenogenetic Stick Insect

open access: yesEcology and Evolution
Parents can invest in offspring by transferring environmental factors, such as nutrients or diet‐derived defence chemicals, into eggs or embryos. However, in systems where females can reproduce facultatively without a male (facultative parthenogenesis ...
Ana Caroline Oliveira Vasconcelos   +2 more
doaj   +1 more source

SDF‐1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy‐Enhanced Stress Granule Scavenging

open access: yesAdvanced Science, EarlyView.
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long   +12 more
wiley   +1 more source

Genetic parameters for direct and maternal genetic components of calving ease in Korean Holstein Cattle using animal models [PDF]

open access: yesAnimal Bioscience
Objective We investigated genetic parameters of calving ease (CE) using several animal models in Korean Holstein and searched for suitable models for routine evaluation of CE.
Mahboob Alam   +11 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

Population density effects on gamete traits and fertilisation dynamics under varying sperm environments in mussels

open access: yesEcology and Evolution
Gamete traits can vary widely among species, populations and individuals, influencing fertilisation dynamics and overall reproductive fitness. Sexual selection can play an important role in determining the evolution of gamete traits with local ...
Craig D. H. Sherman   +4 more
doaj   +1 more source

Genetic correlation analysis of calving ease and gestation length of Korean Holstein cattle [PDF]

open access: yesAnimal Bioscience
Objective To investigate genetic correlation between calving ease (CE) and gestation length (GL) traits of Korean Holstein cattle to understand genetic structures of these two traits and their potential implications.
Mahboob Alam   +11 more
doaj   +1 more source

Maternal mortality in high HIV prevalence countries: a critical analysis of the MMEIG methodology for estimating maternal mortality [PDF]

open access: yes, 2012
Includes abstract.Includes bibliographical references.The main objective of this research is to analyse critically the methodology used by the Maternal Mortality Estimation Inter-Agency Group (MMEIG) to estimate maternal mortality in countries with high ...
Gotora, Tendai
core   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

open access: yesAdvanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao   +5 more
wiley   +1 more source

Effectiveness of the Expanded Maternal and Neonatal Survival Program in the Reduction of Maternal Mortality in Tegal, Central Java [PDF]

open access: yes, 2016
Background: Maternal mortality rate is one of the sensitive indicators of population health in a country. Various measures have been implemented to reduce maternal mortality rate, including the Expanding Maternal And Neonatal Survival (EMAS) program ...
Demartoto, Argyo   +2 more
core  

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