Results 81 to 90 of about 443,472 (266)

Estudo genético-quantitativo de características de crescimento na raça Tabapuã A genetic-quantitative study of growth traits in Tabapuã cattle

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
Estimaram-se os componentes de variância e covariância e as herdabilidades para os efeitos direto e materno, as correlações entre os efeitos direto e materno e a fração de ambiente permanente na variação total, utilizando-se o aplicativo MTDFREML, para ...
S.H.A. Ribeiro, J.C.C. Pereira, R.S. Verneque, M.A. Silva, J.A.G. Bergmann, F.S. Marques   +5 more
doaj   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Context-specific “silver-spoon” effects of wetlands, climate, and temperature on lifetime fitness in a short-lived temperate-breeding migratory songbird

Frontiers in Bird Science
Drivers of global change are creating strongly contrasting early life conditions for developing offspring, which may have carry-over effects on lifetime fitness.
Lisha L. Berzins, Russell D. Dawson, Robert G. Clark, Robert G. Clark   +3 more
doaj   +1 more source

Estimation of genetic potential for growth traits in Anatolian buffaloes [PDF]

Revista Brasileira de Zootecnia
To conduct an optimal breeding and selection program, it is necessary to understand the genetic underpinnings of the desired traits. Early growth is an indicator of future success in the production and reproduction of buffaloes.
Yusuf Kaplan, Samet Çinkaya, Mustafa Demirtaş, Mustafa Tekerli   +3 more
doaj   +2 more sources

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

Parental Effect on Agronomic and Olive Oil Traits in Olive Progenies from Reciprocal Crosses

Plants
Olive growing is undergoing a transition from traditional cultivation systems to a more technological model characterized by increased mechanization and a higher density of plants per hectare.
Hristofor Miho, Mihad Atallah, Carlos Trapero, Georgios Koubouris, Pedro Valverde   +4 more
doaj   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Maternal Provisioning of Offspring With Defence Chemicals in a Facultatively Parthenogenetic Stick Insect

Ecology and Evolution
Parents can invest in offspring by transferring environmental factors, such as nutrients or diet‐derived defence chemicals, into eggs or embryos. However, in systems where females can reproduce facultatively without a male (facultative parthenogenesis ...
Ana Caroline Oliveira Vasconcelos, Lewis Adler, Russell Bonduriansky   +2 more
doaj   +1 more source

Genetic parameters for direct and maternal genetic components of calving ease in Korean Holstein Cattle using animal models [PDF]

Animal Bioscience
Objective We investigated genetic parameters of calving ease (CE) using several animal models in Korean Holstein and searched for suitable models for routine evaluation of CE.
Mahboob Alam, Jae-Gu Lee, Chang-Gwon Dang, Seung-Soo Lee, Sang-Min Lee, Ha-Seung Seong, Mina Park, Jaebeom Cha, Eun-Ho Kim, Hyungjun Song, Seokhyun Lee, Joonho Lee   +11 more
doaj   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source