Results 41 to 50 of about 1,019,538 (305)
New Approaches to Optimize Somatic Embryogenesis in Maritime Pine
Frontiers in Plant Science, 2019 Maritime pine (Pinus pinaster Aiton) is a coniferous native of the Mediterranean basin. Because of its adaptability to a wide range of environmental conditions, the species have become a model for studies in coniferous forest management and functional ...
Isabel Arrillaga +5 more
doaj +1 more source
Maternal atopy and offspring epigenome-wide methylation signature
Epigenetics, 2021 The increase in the prevalence of allergic diseases is believed to partially depend on environmental changes. DNA methylation is a major epigenetic mechanism, which is known to respond to environmental factors.
Hanna Danielewicz +9 more
doaj +1 more source
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007 Estimaram-se os componentes de variância e covariância e as herdabilidades para os efeitos direto e materno, as correlações entre os efeitos direto e materno e a fração de ambiente permanente na variação total, utilizando-se o aplicativo MTDFREML, para ...
S.H.A. Ribeiro +5 more
doaj +1 more source
Activation of 5-HT 2A Receptor Disrupts Rat Maternal Behavior [PDF]
, 2019 Serotonin 5-HT2A receptor is widely distributed in the central nervous system and plays an important role in sensorimotor function, emotion regulation, motivation, executive control, learning and memory. We investigated its role in rat maternal behavior,
Davis, Collin +3 more
core +1 more source
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Frontiers in Plant ScienceIntroductionTouch by neighboring plants is a common but overlooked environmental variable for plants, especially in dense vegetation. In addition, shade is inevitable for understory plants.
Linya Xing +6 more
doaj +1 more source
Maternal Prepregnancy 5-Hydroxytryptamine Exposure Affects the Early Development of the Fetus
Frontiers in Physiology, 2022 In recent decades, the increasing incidence of depression has contributed to an increase in the use of serotonergic drugs, such as antidepressants, which predisposes humans to serotonin syndrome.
Yu Han +12 more
doaj +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Frontiers in Neuroscience, 2020 ObjectivePrior studies have shown that there is an inverse association between birth weight and stroke in adulthood; however, whether such association is causal remains yet known and those studies cannot distinguish between the direct fetal effect and ...
Ting Wang +10 more
doaj +1 more source