Results 31 to 40 of about 440,897 (265)

The Effect of Maternal Obesity on the Offspring [PDF]

open access: yesClinical Obstetrics & Gynecology, 2014
Maternal obesity is inextricably linked to adverse health outcomes for the mother and her children. The peripartum period is a critical period of risk. In this chapter, we examine the importance of maternal prepregnancy weight status, gestational weight gain, breastfeeding, and postpartum weight loss in relation to subsequent risk for maternal obesity ...
Christine B, Williams   +2 more
openaire   +2 more sources

Separating Paternal and Maternal Contributions to Thermal Transgenerational Plasticity

open access: yesFrontiers in Marine Science, 2021
Climate change is rapidly altering the thermal environment in terrestrial and aquatic systems. Transgenerational thermal plasticity (TGP) – which occurs when the temperatures experienced by the parental generation prior to the fertilization of gametes ...
Sarah L. Chang   +3 more
doaj   +1 more source

Immunoglobulin Depletion and Recovery Following Blinatumomab in Infants With KMT2A‐Rearranged ALL

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Adding blinatumomab to standard chemotherapy for infants with KMT2A‐rearranged acute B‐cell lymphoblastic leukemia (KMT2A‐r B‐ALL) improves outcomes. Although blinatumomab impairs immunoglobulin G (lgG) production, increasing infection susceptibility, IgG recovery remains poorly understood.
Miguel Vieira Martins   +14 more
wiley   +1 more source

Long-term exposure to diesel exhaust particles induces concordant changes in DNA methylation and transcriptome in human adenocarcinoma alveolar basal epithelial cells

open access: yesEpigenetics & Chromatin
Background Diesel exhaust particles (DEP), which contain hazardous compounds, are emitted during the combustion of diesel. As approximately one-third of the vehicles worldwide use diesel, there are growing concerns about the risks posed by DEP to human ...
Alexandra Lukyanchuk   +6 more
doaj   +1 more source

A loss of heterozygosity, a loss in competition? The effects of inbreeding, pre‐ and postnatal conditions on nestling development

open access: yesEcology and Evolution, 2016
The early developmental trajectory is affected by genetic and environmental factors that co‐depend and interact often in a complex way. In order to distinguish their respective roles, we used canaries (Serinus canaria) of different genetic backgrounds ...
Raïssa A. deBoer   +2 more
doaj   +1 more source

Inter-individual variability of early life stages of a model marine invertebrate with a bi-phasic life cycle is shaped by contrasting oceanographic conditions

open access: yesFrontiers in Marine Science, 2022
Inter-individual variability plays a key role in species resilience. This, however, is difficult to assess in marine invertebrates with complex life cycles due to the inherent difficulty of sampling individuals in oceanic environments throughout their ...
Miguel Costa Leal   +7 more
doaj   +1 more source

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala   +8 more
wiley   +1 more source

Genetic response to selection on reindeer calf weights

open access: yesRangifer, 2003
Selection response was investigated after 11 years of selection in the herding district of Ruvhten Sijte in Sweden (63°N,12°E) by comparing the weights of calves owned by herders applying selection with the weights of calves owned by herders not applying
Lars Rönnegård, Öje Danell
doaj   +1 more source

The role of maternal age and context-dependent maternal effects in the offspring provisioning of a long-lived marine teleost [PDF]

open access: yesRoyal Society Open Science, 2018
Despite evidence of maternal age effects in a number of teleost species, there have been challenges to the assertion that maternal age intrinsically influences offspring quality.
Linsey M. Arnold   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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