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A Framework for Understanding Maternal Immunity

Immunology and Allergy Clinics of North America, 2023
This is an alternative and controversial framing of the data relevant to maternal immunity. It argues for a departure from classical theory to view, interrogate and interpret existing data.
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Maternal immune transfer in mollusc

Developmental & Comparative Immunology, 2015
Maternal immunity refers to the immunity transferred from mother to offspring via egg, playing an important role in protecting the offspring at early life stages and contributing a trans-generational effect on offspring's phenotype. Because fertilization is external in most of the molluscs, oocytes and early embryos are directly exposed to pathogens in
Lingling, Wang   +3 more
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Maternal Immunizations

Obstetrics & Gynecology
Immunization is an essential part of preventive care for adults, including pregnant individuals. Each vaccine recommended for pregnant patients is important for the protection of the maternal–child dyad. Other vaccines provide maternal protection from severe morbidity related to specific pathogens such as pneumococcus, meningococcus, and hepatitis for ...
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Maternal Pertussis Immunization

JAMA, 2014
Pertussis (whooping cough) is a highly contagious and potentially fatal disease that is preventable by vaccination. However, the incidence of whooping cough has increased despite having high vaccine coverage rates in the United States.1 Infants younger than 12 months are especially susceptible to pertussis, and those younger than 2 months—too young to ...
Natalia, Jiménez-Truque   +1 more
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Maternal immunization and malaria in pregnancy

Vaccine, 2003
Malaria in pregnancy is a major cause of poor outcomes for both mother and fetus, and malaria-induced low birth weight (LBW) may kill nearly 400,000 African infants each year. The hallmark of pregnancy malaria due to Plasmodium falciparum is the sequestration of infected erythrocytes (IEs) in the placenta.
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Maternal immune response to pregnancy

Reproduction, Fertility and Development, 1989
The pregnant female is exposed to a variety of potentially immunogenic foreign antigens on her allogenic intra-uterine conceptus. The extent to which maternal antibodies and cell-mediated immune responses to these antigens are relevant to the paradoxical survival of the fetal allograft is not clearly established. The key to the maintenance of pregnancy
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Pharmacists’ role in maternal immunization

Journal of the American Pharmacists Association
Maternal immunization is an important strategy to safeguard infants against vaccine-preventable diseases such as pertussis, which poses a significant economic burden on the health care system. Although the Tetanus, Diphtheria, and Pertussis vaccine has been recommended for pregnant individuals since 2018, uptake varies widely across Canadian provinces.
Kyle J. Gomes   +2 more
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Maternal antibodies' role in immunity

Science, 2017
The investigation on the epidemiology of all known human influenza cases worldwide by K. M. Gostic et al. (“Potent protection against H5N1 and H7N9 influenza via childhood hemagglutinin imprinting,” Research Article, 11 November 2016, p.
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Maternal Immunization: An Update for Pediatricians

Pediatric Annals, 2013
CME Educational Objectives 1. Discuss the current recommendations for vaccination during pregnancy in the United States. 2.
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The Influence of Maternal Immunization on Infant Immune Responses

Journal of Comparative Pathology, 2007
The vaccination of human mothers during pregnancy leads to transplacental transfer of antibody which can provide protection to the neonate during early life. This active transfer is a receptor-mediated event with preferential transport of antibody of the IgG1 and IgG3 subclasses via the FcR(n) receptor.
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