Results 171 to 180 of about 1,453,231 (297)

Maternal separation increases anxiety-like phenotypes, fear responses, and alters <i>Bdnf</i> methylation in a predator odor exposure model of early life adversity. [PDF]

Neurobiol Stress
Collins NJ, Ross SE, Prysakar M, Bigham O, Ayers LW, Rosen JB, Roth TL.   +6 more
europepmc   +1 more source

Enhanced harm detection following maternal separation: Transgenerational transmission and reversibility by inhaled amiloride. [PDF]

Sci Adv, 2023
Battaglia M, Rossignol O, Lorenzo LE, Deguire J, Godin AG, D'Amato FR, De Koninck Y.   +6 more
europepmc   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Combined maternal separation and limited bedding-nesting increase goal tracking, delay discounting, and impulsive action, and moderate sign-tracking-perseverance associations in male rats. [PDF]

BMC Neurosci
Cifuentes J, Arias-Higuera M, Acevedo-Triana C, Hylin MJ, Pozzo-Miller L, Hurtado-Parrado C.   +5 more
europepmc   +1 more source

Maternal separation and its developmental consequences on anxiety and parvalbumin interneurons in the amygdala. [PDF]

J Neural Transm (Vienna), 2023
Abraham M, Schmerder K, Hedtstück M, Bösing K, Mundorf A, Freund N.   +5 more
europepmc   +1 more source

N-acetylcysteine Restores Impaired Dentate Gyrus Neurogenesis in a Neonatal Maternal Separation Rat Model. [PDF]

Exp Neurobiol
Kim HB, Kim YJ, Lim HM, Suh SW, Lee JH, Lee CJ, Woo RS.   +6 more
europepmc   +1 more source

Maternal separation differentially modulates early pathology by sex in 5xFAD Alzheimer's disease-transgenic mice. [PDF]

Brain Behav Immun Health, 2023
Garcia MG, Paulus A, Vázquez-Reyes S, Klementieva O, Gouras GK, Bachiller S, Deierborg T.   +6 more
europepmc   +1 more source

The quantification and epistemology of medicines use and polypharmacy tested in an observational study

British Journal of Clinical Pharmacology, EarlyView.
Definitions of ‘medicines use’ and ‘polypharmacy’ may refer to all medicines, regular long‐term medicines or another subset. Valid definitions of medicines use should incorporate type of use (long term, short course and as needed [PRN]), changes in use (start, stop and dose change) and a description of temporal examination (cross‐sectional or ...
Lorna Pairman, Paul Chin, Matthew Doogue
wiley   +1 more source

Dysfunction of the paraventricular thalamus-prelimbic cortex circuit underlies maternal separation-induced deficits in contagious pain. [PDF]

Sci Adv
Zhang Z, Gong Y, Su XY, Su XY, Deng Y, Du R, Li CL, Wang Y, Song XL, Jiang Q, Li Y, Jian Y, Tong X, Wang GH, Chen J, Xu TL, Liu MG, Jiang F.   +17 more
europepmc   +1 more source

Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women

British Journal of Clinical Pharmacology, EarlyView.
Aim This paper aims to evaluate the plasma and breast milk pharmacokinetics of suvorexant, an orexin receptor antagonist used to treat insomnia at a maximum dose of 20 mg, in healthy lactating women. Methods The paper reports on an open‐label Phase 1 study in 12 healthy lactating women.
Jacqueline McCrea, Andrew Litovsky, Prachi Wickremasingha, Nairita Ghosal, Brad Roadcap, Robert Valesky, Robin Lee, Leea D. Reed, Ming Wang, Wei Fang, Rebecca Wrishko   +10 more
wiley   +1 more source