Results 191 to 200 of about 89,266 (344)

Nationwide Temporal Trends in Adverse Pregnancy Outcomes and Treatments in Systemic Lupus Erythematosus Pregnancy Over Two Decades in Sweden

Arthritis &Rheumatology, EarlyView.
Objective This nationwide descriptive study examined temporal trends in adverse pregnancy outcomes (APOs) and treatments in systemic lupus erythematosus (SLE) pregnancies in Sweden over 2003 to 2022. Methods Using nationwide Swedish registers, we identified 1,417 pregnancies of women with prevalent SLE and delivery dates in 2003 to 2022 and matched ...
Ngoc V. Nguyen, Anna Sandström, Annica Dominicus, Elisabet Svenungsson, Karin Hellgren, Julia F. Simard, Elizabeth V. Arkema   +6 more
wiley   +1 more source

Neonatal Maternal Separation Modifies Proteostasis Marker Expression in the Adult Hippocampus

, 2021
Jorge A. Sierra-Fonseca, Jameel N. Hamdan, Alexis A. Cohen, Sonia M. Cardenas, Sigifredo Saucedo, Gabriel A. Lodoza, Kristin L. Gosselink   +6 more
openalex   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura B. Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore   +19 more
wiley   +1 more source

Environmental enrichment as an intervention to prevent behavioral and neurobiological consequences of maternal separation in rodents: a scope review. [PDF]

Neurobiol Stress
de Sá NF, Assad N, Camarini R, Suchecki D.   +3 more
europepmc   +1 more source

Involvement of oxidative stress in orofacial mechanical pain hypersensitivity following neonatal maternal separation in rats. [PDF]

Sci Rep, 2023
Soma C, Hitomi S, Oshima E, Hayashi Y, Soma K, Shibuta I, Tsuboi Y, Shirakawa T, Kikuiri T, Iwata K, Shinoda M.   +10 more
europepmc   +1 more source

Long Noncoding RNA H19 Mediates STAT3‐Dependent Activation of Keratinocytes and Fibroblasts in Systemic Sclerosis Skin

Arthritis &Rheumatology, EarlyView.
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz, Christopher W. Wasson, Rebecca L. Ross, Francesco Del Galdo   +3 more
wiley   +1 more source

Maternal Separation Alters Open Field-Induced Behaviours In Adult Offspring [PDF]

, 2004
Marmendal, Maarit,, Fahlke, Claudia,
core  

Maternal Separation Differentially Programs Structural and Functional Remodeling of Visceral Adipose Tissue Depots in Mice Exposed to a Post-Weaning High-Fat Diet. [PDF]

Int J Mol Sci
Navarrete J, Vásquez B.
europepmc   +1 more source

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E. M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Maternal separation increases anxiety-like phenotypes, fear responses, and alters <i>Bdnf</i> methylation in a predator odor exposure model of early life adversity. [PDF]

Neurobiol Stress
Collins NJ, Ross SE, Prysakar M, Bigham O, Ayers LW, Rosen JB, Roth TL.   +6 more
europepmc   +1 more source