Umbelliprenin via increase in the MECP2 and attenuation of oxidative stress mitigates the autistic-like behaviors in mouse model of maternal separation stress. [PDF]
Karimi P+4 more
europepmc +1 more source
Neonatal Maternal Separation Alters the Capacity of Adult Neural Precursor Cells to Differentiate into Neurons Via Methylation of Retinoic Acid Receptor Gene Promoter [PDF]
Shuken Boku+7 more
openalex +1 more source
Abstract Background Environmental influence is critical for embryogenesis but is significantly under‐appreciated under lab conditions, which are not typically designed to robustly test environmental variability. Here, we report environmental effects on the developmental phenotype of zebrafish lacking the transcription factor Grainyhead‐like 3 (grhl3 ...
Nishanthi Mathiyalagan+5 more
wiley +1 more source
Distinct ACC Neural Mechanisms Underlie Authentic and Transmitted Anxiety Induced by Maternal Separation in Mice. [PDF]
Jiang J+5 more
europepmc +1 more source
Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters+5 more
wiley +1 more source
Global research trends on maternal separation paradigms as an early life stress model: A bibliometric analysis. [PDF]
Meng X, Bao B, Yue G.
europepmc +1 more source
Methylation of NR3C1 is related to maternal PTSD, parenting stress and maternal medial prefrontal cortical activity in response to child separation among mothers with histories of violence exposure [PDF]
Daniel S. Schechter+14 more
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A head start: The relationship of placental factors to craniofacial and brain development
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver+2 more
wiley +1 more source
Exploration of intervention strategies for alleviating maternal separation anxiety from the perspective of obstetrics and neonatology collaboration. [PDF]
Chen X, Yao L, Pi X.
europepmc +1 more source