Results 281 to 290 of about 2,028,316 (397)

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Combined Effect of Maternal Separation and Early-Life Immune Activation on Brain and Behaviour of Rat Offspring. [PDF]

Biomolecules
Biswas B, Eapen V, Morris MJ, Jones NM.
europepmc   +1 more source

Food for Thought: A Systematic Review and Meta‐Analysis on the Effects of Ultra‐Processed Foods on Cognition in Children and Adolescents

Food Frontiers, EarlyView.
Across 35 studies, this systematic review and meta‐analysis explored the link between ultra‐processed foods (UPFs) and cognition. For children, higher consumption of UPFs was associated with poorer attention, executive functioning, fluid intelligence, and language; for adolescents, higher UPF consumption was associated with poorer executive functioning,
Lan Nguyen, Jared Walters, Bernadette Spies, Amelia Coppus, Jenaya Massie, Thamiris Penteado Bertonha   +5 more
wiley   +1 more source

Duality of Early Life Maternal Separation Effects on Offspring Initial Development and Maternal Neuronal Activation

, 2017
Daniela Rocha Costa Fóscolo, Frederico Sander Mansur Machado, Cândido Celso Coimbra   +2 more
openalex   +1 more source

Clear Waters, Bright Futures: Do Low‐Cost Information Interventions Increase Health Preventive Behaviors

Health Economics, EarlyView.
ABSTRACT Contaminated drinking water poses a significant, long‐term health challenge in developing countries. With the aim of shedding light on the most effective presentation of this information in awareness campaigns, we run a randomized control trial involving 1388 households in Punjab, Pakistan.
Rafi Amir‐ud‐Din, Muhammad Khan, Zahra Murad, Irene Mussio   +3 more
wiley   +1 more source

Effects of Maternal Separation on Effort-based Responding for Sucrose Are Associated with c-Fos Expression in the Nucleus Accumbens Core. [PDF]

Neuroscience
Gildawie KR, Wang K, Budge KE, Byrnes EM.   +3 more
europepmc   +1 more source

Prolonged maternal separation attenuates BDNF‐ERK signaling correlated with spine formation in the hippocampus during early brain development

Journal of Neurochemistry, 2017
Ken-ichi Ohta, Shingo Suzuki, K. Warita, Tomohiro Kaji, T. Kusaka, T. Miki   +5 more
semanticscholar   +1 more source

Insurance Expansion During Pregnancy

Health Economics, EarlyView.
ABSTRACT We analyze how the abolition of cost‐sharing in health insurance affects pregnant women's gross spending on health care services using an exogenous policy change in Switzerland. Using non‐linear regression, we find that the policy slightly increases average gross spending, contrasting policymaker expectations of no impact on demand.
Philip Hochuli, Christian P. R. Schmid
wiley   +1 more source

Effects of early life adverse experiences on the brain: implications from maternal separation

, 2017
Mayumi Nishi, Takayo Sasagawa, Noriko Horii‐Hayashi   +2 more
openalex   +2 more sources

Does maternal separation accelerate maturation of perineuronal nets and parvalbumin-containing inhibitory interneurons in male and female rats?

, 2020
Rick Richardson, Jeremy W. Bowers, Bridget Callaghan, Kathryn Baker   +3 more
openalex   +1 more source