Results 41 to 50 of about 3,172,409 (215)

Differences in Pneumococcal and Haemophilus influenzae Natural Antibody Development in Papua New Guinean Children in the First Year of Life

Frontiers in Immunology, 2021
BackgroundDevelopment of vaccines to prevent disease and death from Streptococcus pneumoniae, and nontypeable Haemophilus influenzae (NTHi), the main pathogens that cause otitis media, pneumonia, meningitis and sepsis, are a global priority.
Kelly M. Martinovich, Tasmina Rahman, Tasmina Rahman, Camilla de Gier, Camilla de Gier, Elke J. Seppanen, Tilda Orami, Caitlyn M. Granland, Jacinta Francis, Mition Yoannes, Karli J. Corscadden, Rebecca Ford, Peter Jacoby, Anita H. J. van den Biggelaar, Anita H. J. van den Biggelaar, Lauren O. Bakaletz, Allan W. Cripps, Deborah Lehmann, Deborah Lehmann, Peter C. Richmond, Peter C. Richmond, William S. Pomat, William S. Pomat, Lea-Ann S. Kirkham, Lea-Ann S. Kirkham, Ruth B. Thornton, Ruth B. Thornton   +26 more
doaj   +1 more source

Follow Up of Maternally Derived Antibodies Titer against Economically Important Viral Diseases of Chicken [PDF]

Poultry Science Journal, 2018
The study was conducted to know the rate of maternally derived antibodies (MDAs) transfer from parents to their offspring and declining the MDAs in their chicks at 0, 7, 14, and 21 days of age against four major poultry viruses like Newcastle disease ...
Ali MZ, Hasan B
doaj   +1 more source

Waning Time of Maternally Derived Anti-Hepatitis A and Anti-Varicella Zoster Virus Antibodies

, 2019
Objective The objective of this study was to investigate the persistence of maternally derived antibodies to hepatitis A (anti-HAV) and varicella zoster (anti-VZV) viruses to determine the optimal time of vaccination of ...
Kocak, Aylin Altay, Civil, Fusun, DUYAN ÇAMURDAN, AYSU, Beyazova, Ufuk, BOZDAYI, GÜLENDAM, Guzelkucuk, Zeliha   +5 more
core   +1 more source

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

Arthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah, Swaleh Hussain, Sara J. T. Guilcher, Lisa M. McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous   +6 more
wiley   +1 more source

Investigation into the safety, and serological responses elicited by delivery of live intranasal vaccines for bovine herpes virus type 1, bovine respiratory syncytial virus, and parainfluenza type 3 in pre-weaned calves

Frontiers in Veterinary Science
Despite the fact that pneumonia remains a leading cause of mortality and morbidity in pre-weaned calves, relatively little is known regarding the effects of the concurrent administration of intranasal pneumonia virus vaccines, particularly in calves with
Anna Flynn, Anna Flynn, Catherine McAloon, Katie Sugrue, Ricki Fitzgerald, Cara Sheridan, Bosco Cowley, Conor McAloon, Emer Kennedy   +8 more
doaj   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

Antibody-mediated protection against respiratory syncytial virus in children

European Respiratory Review
Respiratory syncytial virus (RSV) is a major global pathogen, causing lower respiratory tract disease in at-risk populations including young children. Antibodies form a crucial layer of protection from RSV disease, particularly in immunologically naïve ...
Emma L. Coindy, Claudia Efstathiou, Shubha Talwar, Annick Moureau, Charlotte Vernhes, Peter J.M. Openshaw, Ryan S. Thwaites   +6 more
doaj   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

MATERNALLY DERIVED ANTIBODIES IN AVIAN EGGS AND OFFSPRING: ECOLOGY, LIFE HISTORY, AND DEVELOPMENT [PDF]

, 2009
Mothers can alter offspring phenotypes through a variety of indirect effects, including the deposition of nutrients, hormones, and defense proteins in to the egg. Defense proteins, and antibodies in particular, may be tremendously important for neonatal
Addison, BriAnne Ashley
core   +1 more source

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

Advanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang, Junxiang Ji, Baoxing Dong, Zhenhua Zhu, Xucheng Lv, Peng Chen, Wenqiang Liu, Min Zhou, Shou‐Dong Ye   +8 more
wiley   +1 more source