Results 51 to 60 of about 3,172,409 (215)

Infection- and Vaccine-Induced SARS-CoV-2 Seroprevalence, Japan, 2023

Emerging Infectious Diseases
We assessed SARS-CoV-2 seroprevalence in Japan during July–August 2023, with a focus on 2 key age groups, 0–15 and >80 years. We estimated overall seroprevalence of 45.3% for nucleocapsid antibodies and 95.4% for spike antibodies and found notable ...
Ryo Kinoshita, Sho Miyamoto, Shoko Sakuraba, Jun Sugihara, Motoi Suzuki, Tadaki Suzuki, Daisuke Yoneoka   +6 more
doaj   +1 more source

DURATION OF MATERNALLY DERIVED ANTIBODIES AGAINST PASTEURELLA MULTOCIDA IN COW CALVES [PDF]

Pakistan Veterinary Journal, 2007
The present study was conducted on 30 pregnant, randomly selected Sahiwal cows and their calves, maintained at a Government Livestock farm. The animals were routinely vaccinated against haemorrhagic septicaemia (HS), using alum-precipitated formalin ...
A. K. MAHMOOD, M. A. SHEIKH, S. AKHTAR, G. NABI1 AND H. B. RASHID2
doaj  

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Efficacy of intranasal vaccines containing bovine corona virus or bovine respiratory syncytial virus and parainfluenza virus type 3 in young calves with or without maternally derived antibodies

Veterinary Vaccine
Bovine respiratory syncytial virus, bovine parainfluenza type 3 virus, and bovine corona virus cause respiratory disease in calves during the first weeks of life and protection should be achieved as young as possible to cover the period with the highest ...
Piet Nuijten, Birgit Makoschey, Elias Salem, Mark van Rooij, Geert Vertenten   +4 more
doaj   +1 more source

Interference of maternally-derived antibodies with Survaxyn PRRS MLV vaccination is dependent of the antibody level

, 2021
International audienceWe previously showed that maternally-derived neutralizing antibodies (MDNA) could interfere with the Porcilis PRRS vaccine by decreasing the post-vaccination (PV) immune response and the vaccine efficacy.
Bourry, Olivier, Renson, Patricia, Le Dimna, Mireille, Paboeuf, Frédéric, Mahé, Sophie   +4 more
core  

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Kinetics of the neutralizing antibody response to respiratory syncytial virus infections in a birth cohort [PDF]

, 2013
The kinetics of respiratory syncytial virus (RSV) neutralizing antibodies following birth, primary and secondary infections are poorly defined. The aims of the study were to measure and compare neutralizing antibody responses at different time points in ...
G.F. Medley, C.J. Sande, Sande, Charles J., P.A. Cane, Medley, Graham, Cane, Patricia, Nokes, D. James, Mutunga, M. N., M.N. Mutunga, E.A. Okiro, D.J. Nokes, Okiro, Emelda A.   +11 more
core   +1 more source

Paternal Sperm Gnas‐ICR Epigenetic Programming Contributes to PPP‐Like Phenotypes in Female Offspring

Advanced Science, EarlyView.
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang, Lu Chen, Tiancheng Wu, Yating Li, Hui Wang   +4 more
wiley   +1 more source

Serum IgA and bactericidal immunity against Streptococcus suis serotype 2 is increasing between 2 and 6 weeks of age in a farm with autogenous bacterin vaccination pre-farrowing, while specific maternal IgG is decreasing

Porcine Health Management
Background Neonatal piglets take up maternal IgG and IgA antibodies via colostrum. Streptococcus suis (S. suis) is a major porcine pathogen that may cause invasive infections in the first ten weeks of life, leading to septicemia, polyarthritis, and ...
Theresa Middendorf, Josepha Hallbauer, Matthias Horn, Silke Lehnert, Karoline Rieckmann, Alexander Maas, Wieland Schrödl, Christoph G. Baums   +7 more
doaj   +1 more source