Results 1 to 10 of about 90,448 (261)

SARS-CoV-2 viremia and COVID-19 mortality: A prospective observational study

PLoS ONE, 2023
Background SARS-CoV-2 viremia has been found to be a potential prognostic factor in patients hospitalized for COVID-19. Objective We aimed to assess the association between SARS-CoV-2 viremia and mortality in COVID-19 hospitalized patients during ...
Valeria Micheli, Anna Bernasconi, Pietro Pinoli   +2 more
exaly   +2 more sources

Persistent HIV-1 Viremia on Antiretroviral Therapy: Measurement and Mechanisms

Frontiers in Microbiology, 2019
HIV-1 viremia persists at low-levels despite clinically effective antiretroviral therapy (ART). Here we review new methods to quantify and characterize persistent viremia at the single genome level, and discuss the mechanisms of persistence including ...
Jana Jacobs, John Mellors, Elias Halvas   +2 more
exaly   +2 more sources

Virological failure and all-cause mortality in HIV-positive adults with low-level viremia during antiretroviral treatment

PLoS ONE, 2017
Objective Although most HIV-infected individuals achieve undetectable viremia during antiretroviral therapy (ART), a subset have low-level viremia (LLV) of varying duration and magnitude. The impact of LLV on treatment outcomes is unclear.
Magnus Gisslén, Per Björkman, Olof Elvstam   +2 more
exaly   +2 more sources

Kidney Transplant-Associated Viral Infection Rates and Outcomes in a Single-Centre Cohort

Viruses, 2022
Background: Opportunistic infections remain a significant cause of morbidity and mortality after kidney transplantation. This retrospective cohort study aimed to assess the incidence and predictors of post-transplant DNA virus infections (CMV, EBV, BKV ...
Kairi Pullerits, Shona Garland, Sharmilee Rengarajan, Malcolm Guiver, Rajkumar Chinnadurai, Rachel J. Middleton, Chukwuma A. Chukwu, Philip A. Kalra   +7 more
doaj   +1 more source

Clonally expanded HIV-1 proviruses with 5′-leader defects can give rise to nonsuppressible residual viremia

Journal of Clinical Investigation, 2023
Background Antiretroviral therapy (ART) halts HIV-1 replication, decreasing viremia to below the detection limit of clinical assays. However, some individuals experience persistent nonsuppressible viremia (NSV) originating from CD4+ T cell clones ...
J. White, Fengting Wu, Saif Yasin, M. Moskovljevic, Joseph Varriale, F. Dragoni, Angelica Camilo Contreras, Jiayi Duan, Mei-yun Zheng, Ndeh F. Tadzong, Heer B Patel, J. M. C. Quiambao, K. Rhodehouse, Hao Zhang, J. Lai, Subul A. Beg, Michael Delannoy, Christin Kilcrease, C. Hoffmann, S. Poulin, F. Chano, C. Tremblay, Jerald P. Cherian, P. Barditch‐Crovo, N. Chida, R. Moore, M. Summers, R. Siliciano, J. Siliciano, F. Simonetti   +29 more
semanticscholar   +1 more source

Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar

Viruses, 2021
Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle East and North Africa (MENA) region and other parts of Asia are ...
Doua Abdelrahman, Duaa W. Al-Sadeq, Maria K. Smatti, Sara A. Taleb, Raed O AbuOdeh, Enas S. Al-Absi, Asmaa A. Al-Thani, Peter. V. Coyle, Nader Al-Dewik, Ahmed A. Al Qahtani, Hadi M. Yassine, Gheyath K. Nasrallah   +11 more
doaj   +1 more source

SARS-CoV-2 Viremia is Associated with COVID-19 Severity and Predicts Clinical Outcomes.

Clinical Infectious Diseases, 2021
BACKGROUND SARS-CoV-2 viral RNA (vRNA) is detected in the bloodstream of some patients with COVID-19 ("RNAemia") but it is not clear whether this RNAemia reflects viremia (i.e., virus particles) and how RNAemia/viremia is related to host immune responses
J. Jacobs, W. Bain, Asma Naqvi, Brittany Staines, Priscila M S Castanha, Haopu Yang, V. Boltz, S. Barratt-Boyes, E. Marques, S. Mitchell, B. Methé, T. Olonisakin, G. Haidar, Thomas W. Burke, Elizabeth W. Petzold, T. Denny, C. Woods, B. McVerry, Janet S. Lee, Simon C Watkins, C. S. St Croix, A. Morris, Mary F. Kearney, M. Ladinsky, P. Bjorkman, G. Kitsios, J. Mellors   +26 more
semanticscholar   +1 more source

The role of different viral biomarkers on the management of chronic hepatitis B [PDF]

Clinical and Molecular Hepatology, 2023
Chronic hepatitis B infection is a major public health challenge. With the advancement in technology, various components of the viral cycle can now be measured in the blood to assess viral activity.
Lung-Yi Mak, Rex Wan-Hin Hui, James Fung, Wai Kay Seto, Man-Fung Yuen   +4 more
doaj   +1 more source

The Longest Persistence of Viable SARS-CoV-2 With Recurrence of Viremia and Relapsing Symptomatic COVID-19 in an Immunocompromised Patient—A Case Study

Open Forum Infectious Diseases, 2021
Background Immunocompromised patients show prolonged shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in nasopharyngeal swabs.
Chiara Sepulcri, C. Dentone, M. Mikulska, B. Bruzzone, A. Lai, D. Fenoglio, F. Bozzano, A. Bergna, A. Parodi, T. Altosole, E. Delfino, G. Bartalucci, A. Orsi, A. di Biagio, G. Zehender, F. Ballerini, S. Bonora, A. Sette, R. De Palma, G. Silvestri, A. De Maria, M. Bassetti   +21 more
semanticscholar   +1 more source

Understanding the mechanisms for COVID-19 vaccine’s protection against infection and severe disease

Expert Review of Vaccines, 2023
Introduction Multiple COVID-19 vaccines have been approved and employed in the fight against the pandemic. However, these vaccines have limited long-term effectiveness against severe cases and a decreased ability to prevent mild disease.
Huijie Yang, Ying Xie, Changgui Li
doaj   +1 more source