Results 11 to 20 of about 90,448 (261)

SARS-CoV-2 Viremia is Associated with Distinct Proteomic Pathways and Predicts COVID-19 Outcomes

medRxiv, 2021
Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) plasma viremia has been associated with severe disease and death in coronavirus disease 2019 (COVID-19) in small-scale cohort studies.
Yijia Li, Alexis M. Schneider, Arnav Mehta, Moshe Sade-Feldman, Kyle R. Kays, M. Gentili, Nicole C. Charland, Anna L. K. Gonye, Irena Gushterova, Hargun K. Khanna, T. LaSalle, Kendall M. Lavin-Parsons, B. M. Lilley, Carl L. Lodenstein, Kasidet Manakongtreecheep, J. Margolin, Brenna N. Mckaig, B. Parry, Maricarmen Rojas-Lopez, Brian C. Russo, Nihaarika Sharma, J. Tantivit, M. Thomas, J. Regan, James Flynn, A. Villani, N. Hacohen, M. Goldberg, M. Filbin, Jonathan Z. Li   +29 more
semanticscholar   +1 more source

Occurrence of SARS-CoV-2 viremia is associated with genetic variants of genes related to COVID-19 pathogenesis

Frontiers in Medicine, 2023
IntroductionSARS-CoV-2 viral load has been related to COVID-19 severity. The main aim of this study was to evaluate the relationship between SARS-CoV-2 viremia and SNPs in genes previously studied by our group as predictors of COVID-19 severity.Materials
Emilia Roy-Vallejo, Emilia Roy-Vallejo, Sara Fernández De Córdoba-Oñate, Pablo Delgado-Wicke, Ana Triguero-Martínez, Ana Triguero-Martínez, Nuria Montes, Nuria Montes, Rosa Carracedo-Rodríguez, Nelly Zurita-Cruz, Ana Marcos-Jiménez, Ana Marcos-Jiménez, Amalia Lamana, José María Galván-Román, José María Galván-Román, Gonzalo Villapalos García, Gonzalo Villapalos García, Pablo Zubiaur, Pablo Zubiaur, Marianela Ciudad, Laura Rabes, Marta Sanz, Carlos Rodríguez, Almudena Villa, Jesús Álvarez Rodríguez, Celeste Marcos, Julia Hernando, Paula Díaz-Fernández, Paula Díaz-Fernández, Francisco Abad, Francisco Abad, Francisco Abad, Ignacio de los Santos, Ignacio de los Santos, Ignacio de los Santos, Diego A. Rodríguez Serrano, Rosario García-Vicuña, Rosario García-Vicuña, Carmen Suárez Fernández, Carmen Suárez Fernández, Carmen Suárez Fernández, Rosa P. Gomariz, Cecilia Muñoz-Calleja, Cecilia Muñoz-Calleja, Cecilia Muñoz-Calleja, Elena Fernández-Ruiz, Elena Fernández-Ruiz, Elena Fernández-Ruiz, Isidoro González-Álvaro, Isidoro González-Álvaro, Laura Cardeñoso, Laura Cardeñoso, the PREDINMUN-COVID Group   +52 more
doaj   +1 more source

Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruption

Cell Reports, 2022
SUMMARY The HIV-1 reservoir is composed of cells harboring latent proviruses that have the potential to contribute to viremia upon antiretroviral treatment (ART) interruption. While this reservoir is known to be maintained by clonal expansion of infected
B. Cole, L. Lambrechts, Z. Boyer, Ytse Noppe, M. De Scheerder, John-Sebastian Eden, B. Vrancken, T. Schlub, S. McLaughlin, L. Frenkel, S. Palmer, L. Vandekerckhove   +11 more
semanticscholar   +1 more source

VIREMIA IN HUMAN POLIOMYELITIS [PDF]

Journal of Experimental Medicine, 1954
Poliomyelitis virus was isolated from the blood of 6 of 33 individuals infected with a Type 1 strain. Of the 27 negative for viremia, 18 already had Type 1 antibodies. Type 1 virus was isolated from the throat swabs of all 6 who had viremia, and from the 5 rectal swabs tested.
D M, HORSTMANN, R W, McCOLLUM, A D, MASCOLA   +2 more
openaire   +2 more sources

Quantitative analysis of viremia and viral shedding in pigs infected experimentally with classical swine fever virus isolates obtained from recent outbreaks in Japan

Veterinary Research, 2023
Although classical swine fever occurred in September 2018 for the first time in 26 years, its virulence is thought to be moderate based on field observations by veterinary authorities and our previous experimental infections.
Katsuhiko Fukai, Tatsuya Nishi, Kentaro Masujin, Manabu Yamada, Mitsutaka Ikezawa   +4 more
doaj   +1 more source

Long‐Term Study of Hepatitis Delta Virus Infection at Secondary Care Centers: The Impact of Viremia on Liver‐Related Outcomes

Hepatology, 2020
Hepatitis delta virus (HDV) infection is associated with fast progression to liver cirrhosis and liver complications. Previous studies have, however, been mainly from tertiary care centers, with risk for referral bias toward patients with worse outcomes.
Habiba Kamal, G. Westman, K. Falconer, A. Duberg, O. Weiland, Susanna Haverinen, R. Wejstål, T. Carlsson, Christian Kampmann, Simon B. Larsson, P. Björkman, A. Nystedt, K. Cardell, S. Svensson, S. Stenmark, H. Wedemeyer, S. Aleman   +16 more
semanticscholar   +1 more source

Duration of SARS-CoV-2 viremia and its correlation to mortality and inflammatory parameters in patients hospitalized for COVID-19: a cohort study

Diagnostic microbiology and infectious disease, 2021
Background SARS-CoV-2 viremia at admission is associated with high risk for mortality. However, longitudinal data on viremia duration are limited.
Karl Hagman, M. Hedenstierna, Johan Rudling, P. Gille-Johnson, B. Hammas, Malin Grabbe, Jan Jakobsson, Joakim Dillner, Johan Ursing   +8 more
semanticscholar   +1 more source

MARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination

EMBO Journal, 2021
Viremia in the vertebrate host is a major determinant of arboviral reservoir competency, transmission efficiency, and disease severity. However, immune mechanisms that control arboviral viremia are poorly defined. Here, we identify critical roles for the
Kathryn S Carpentier, R. Sheridan, C. Lucas, Bennett J Davenport, Frances S Li, Erin D. Lucas, M. McCarthy, Glennys V. Reynoso, N. A. May, B. Tamburini, J. Hesselberth, H. Hickman, T. Morrison   +12 more
semanticscholar   +1 more source

Evaluation of Virulence in Cynomolgus Macaques Using a Virus Preparation Enriched for the Extracellular Form of Monkeypox Virus

Viruses, 2022
The 2022 global human monkeypox outbreak emphasizes the importance of maintaining poxvirus research, including enriching a basic understanding of animal models for developing and advancing therapeutics and vaccines.
Eric M. Mucker, Josh D. Shamblin, Arthur J. Goff, Todd M. Bell, Christopher Reed, Nancy A. Twenhafel, Jennifer Chapman, Marc Mattix, Derron Alves, Robert F. Garry, Lisa E. Hensley   +10 more
doaj   +1 more source

HIV-1 Viremia Not Suppressible By Antiretroviral Therapy Can Originate from Large T-Cell Clones Producing Infectious Virus

bioRxiv, 2020
BACKGROUND HIV-1 viremia that is not suppressed by combination antiretroviral therapy (ART) is generally attributed to incomplete medication adherence and/or drug resistance.
E. Halvas, K. Joseph, L. Brandt, Shuang Guo, M. Sobolewski, J. Jacobs, C. Tumiotto, John K Bui, J. Cyktor, B. Keele, G. Morse, Michael J. Bale, W. Shao, Mary F. Kearney, J. Coffin, J. Rausch, Xiaolin Wu, S. Hughes, J. Mellors   +18 more
semanticscholar   +1 more source