Results 31 to 40 of about 90,448 (261)

Contraception use and HIV outcomes among women initiating dolutegravir‐containing antiretroviral therapy in Kenya: a retrospective cohort study

Journal of the International AIDS Society, 2022
Introduction The rollout of dolutegravir (DTG) in low‐ and middle‐income countries was disrupted by a potential association reported with periconceptional DTG exposure among women living with HIV (WLHIV) and infant neural tube defects.
John M. Humphrey, Victor Omodi, Caitlin Bernard, Mercy Maina, Julie Thorne, Ann Mwangi, Kara Wools‐Kaloustian, Rena C. Patel   +7 more
doaj   +1 more source

The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia

mBio, 2022
Persistent SARS-CoV-2 replication and systemic dissemination are linked to increased COVID-19 disease severity and mortality. However, the precise immune profiles that track with enhanced viral clearance, particularly from systemic RNAemia, remain ...
Chuangqi Wang, Yijia Li, Paulina Kaplonek, Matteo Gentili, Stephanie Fischinger, Kathryn A. Bowman, Moshe Sade-Feldman, Kyle R. Kays, James Regan, James P. Flynn, Marcia B. Goldberg, Nir Hacohen, Michael R. Filbin, Douglas A. Lauffenburger, Galit Alter, Jonathan Z. Li   +15 more
doaj   +1 more source

Virological suppression and clinical management in response to viremia in South African HIV treatment program: A multicenter cohort study

PLoS Medicine, 2020
Background Uptake of antiretroviral treatment (ART) is expanding rapidly in low- and middle-income countries (LMIC). Monitoring of virological suppression is recommended at 6 months of treatment and annually thereafter.
L. Hermans, S. Carmona, M. Nijhuis, H. Tempelman, D. Richman, Michelle A. Moorhouse, D. Grobbee, W. Venter, A. Wensing   +8 more
semanticscholar   +1 more source

High Incidence of Chikungunya Virus and Frequency of Viremic Blood Donations during Epidemic, Puerto Rico, USA, 2014

Emerging Infectious Diseases, 2016
Chikungunya virus (CHIKV) caused large epidemics throughout the Caribbean in 2014. We conducted nucleic acid amplification testing (NAAT) for CHIKV RNA (n = 29,695) and serologic testing for IgG against CHIKV (n = 1,232) in archived blood donor samples ...
Graham Simmons, Vanessa Brès, Kai Lu, Nathan M. Liss, Donald J. Brambilla, Kyle R. Ryff, Roberta Bruhn, Edwin Velez, Derrek Ocampo, Jeffrey M. Linnen, Gerardo Latoni, Lyle R. Petersen, Phillip Williamson, Edward L. Murphy   +13 more
doaj   +1 more source

Dengue Viremia Kinetics in Asymptomatic and Symptomatic infection.

International Journal of Infectious Diseases, 2020
BACKGROUND Dengue infection is a global health threat. While symptomatic cases contribute to morbidity and mortality, the majority of infected people are asymptomatic but serve as important reservoir.
P. Matangkasombut, Kajohnpong Manopwisedjaroen, Nada Pitabut, Sasikanya Thaloengsok, S. Suraamornkul, Tawatchai Yingtaweesak, V. Duong, A. Sakuntabhai, R. Paul, P. Singhasivanon   +9 more
semanticscholar   +1 more source

The Potential Harm of Cytomegalovirus Infection in Immunocompetent Critically Ill Children

Frontiers in Pediatrics, 2018
Cytomegalovirus (CMV) is a ubiquitous infection that causes disease in congenitally infected children and immunocompromised patients. Although nearly all CMV infections remain latent and asymptomatic in immunologically normal individuals, numerous ...
Raidan Alyazidi, Raidan Alyazidi, Srinivas Murthy, Jennifer A. Slyker, Soren Gantt   +4 more
doaj   +1 more source

Splenunculus mimicking splenomegaly in a patient with synchronous herpes simplex 1 viremia and myelosuppression

Clinical Case Reports, 2022
Splenunculus, or congenital accessory spleen, is a benign anatomical variation, and is rarely of clinical consideration in routine clinical practice.
Dion A. Paul, Paul Bao Duy La, Joshua Haron Abasszade   +2 more
doaj   +1 more source

Higher Plasma Viremia in the Febrile Phase Is Associated With Adverse Dengue Outcomes Irrespective of Infecting Serotype or Host Immune Status: An Analysis of 5642 Vietnamese Cases

Clinical Infectious Diseases, 2020
Background One of the generally accepted constructs of dengue pathogenesis is that clinical disease severity is at least partially dependent upon plasma viremia, yet data on plasma viremia in primary versus secondary infections and in relation to ...
N. L. Vuong, N. Quyen, N. T. Tien, N. Tuan, D. T. Kien, P. K. Lam, D. Tam, T. Van Ngoc, S. Yacoub, T. Jaenisch, R. Geskus, C. Simmons, B. Wills   +12 more
semanticscholar   +1 more source

A importância do diagnóstico precoce da leucemia viral felina

Pubvet
Nos últimos anos, os felinos têm ganhado espaço nos lares brasileiros, com um total de 27,1 milhões de gatos em lares domésticos, de acordo com o Censo Pet IPB em 2021.
Julia Costa Pereira dos Santos, Júlia Thuler, Anna Clara Alves, Laura Ponciano Venciguerra, Ana Carolina Degli Esposti, Alice Bueno Tarelho, Yasmin Naiadini Centeno Borges, Douglas Segalla Caragelasco   +7 more
doaj   +1 more source

Morphological studies in a model for dengue-2 virus infection in mice

Memorias do Instituto Oswaldo Cruz, 2006
One of the main difficulties in studying dengue virus infection in humans and in developing a vaccine is the absence of a suitable animal model which develops the full spectrum of dengue fever, dengue haemorrhagic fever, and dengue shock syndrome.
Ortrud Monika Barth, Débora Ferreira Barreto, Marciano Viana Paes, Christina Maeda Takiya, Angela Teixeira Pinhão, Hermann Gonçalves Schatzmayr   +5 more
doaj   +1 more source