Results 31 to 40 of about 72,487 (242)

Buckling of a growing tissue and the emergence of two-dimensional patterns [PDF]

, 2013
The process of biological growth and the associated generation of residual stress has previously been considered as a driving mechanism for tissue buckling and pattern selection in numerous areas of biology.
Jensen, OE, King, JR, Nelson, MR
core   +1 more source

Hydrogen peroxide induced cell death: One or two modes of action?

Heliyon, 2015
Imlay and Linn show that exposure of logarithmically growing Escherichia coli to hydrogen peroxide (H2O2) leads to two kinetically distinguishable modes of cell killing.
Lionel Uhl, Audrey Gerstel, Maialène Chabalier, Sam Dukan   +3 more
doaj   +1 more source

Multistage feedback-driven compartmental dynamics of hematopoiesis

iScience, 2021
Summary: Human hematopoiesis is surprisingly resilient to disruptions, providing suitable responses to severe bleeding, long-lasting immune activation, and even bone marrow transplants.
Nathaniel Vincent Mon Père, Tom Lenaerts, Jorge Manuel dos Santos Pacheco, David Dingli   +3 more
doaj   +1 more source

Excitable dynamics of flares and relapses in autoimmune diseases

iScience, 2023
Summary: Many autoimmune disorders exhibit flares in which symptoms erupt and then decline, as exemplified by multiple sclerosis (MS) in its relapsing-remitting form.
Yael Lebel, Tomer Milo, Alon Bar, Avi Mayo, Uri Alon   +4 more
doaj   +1 more source

Optimal experimental design for mathematical models of haematopoiesis. [PDF]

, 2021
The haematopoietic system has a highly regulated and complex structure in which cells are organized to successfully create and maintain new blood cells.
Iniguez, Abdon, Jena, Nilamani, Lander, Arthur D, Liu, Zhong-Ying, Lomeli, Luis Martinez, Lowengrub, John S, Minin, Vladimir N, Shahbaba, Babak, Tata, Prasanthi, Van Etten, Richard   +9 more
core   +1 more source

Special issue: mathematical methods in the biosciences

Mathematical Biosciences and Engineering, 2020
The special issue is available from: https://www.aimspress.com/newsinfo/1079.html/.
Alberto A. Pinto, Jorge P. Zubelli
openaire   +3 more sources

A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer

iScience, 2020
Summary: Tumor heterogeneity and cisplatin resistance are major causes of tumor relapse and poor survival. Here, we show that in lung cancer, interaction between paxillin (PXN) and integrin β4 (ITGB4), components of the focal adhesion (FA) complex ...
Atish Mohanty, Arin Nam, Alex Pozhitkov, Lu Yang, Saumya Srivastava, Anusha Nathan, Xiwei Wu, Isa Mambetsariev, Michael Nelson, A.R. Subbalakshmi, Linlin Guo, Mohd W. Nasser, Surinder K. Batra, John Orban, Mohit Kumar Jolly, Erminia Massarelli, Prakash Kulkarni, Ravi Salgia   +17 more
doaj   +1 more source

Reversible adhesion by type IV pili leads to formation of permanent localized clusters

iScience, 2022
Summary: The formation of long-lived, multicellular clusters is a fundamental step in the physiopathology of many disease-causing bacteria. Experiments on abiotic surfaces suggest that bacterial colonization, including initial cluster formation, requires
María Victoria Pepe, Celeste Dea, Camila Genskowsky, Darío Capasso, Mara Sabrina Roset, Adriana Valeria Jäger, Fernando Peruani, Arlinet Kierbel   +7 more
doaj   +1 more source

Targeting metabolic fluxes reverts metastatic transitions in ovarian cancer

iScience, 2023
Summary: The formation of spheroids during epithelial ovarian cancer progression is correlated with peritoneal metastasis, disease recurrence, and poor prognosis.
Garhima Arora, Mallar Banerjee, Jimpi Langthasa, Ramray Bhat, Samrat Chatterjee   +4 more
doaj   +1 more source

Epidemiological models with parametric heterogeneity: Deterministic theory for closed populations [PDF]

, 2012
We present a unified mathematical approach to epidemiological models with parametric heterogeneity, i.e., to the models that describe individuals in the population as having specific parameter (trait) values that vary from one individuals to another ...
Novozhilov, Artem S.
core   +1 more source