Results 41 to 50 of about 327,393 (318)
Nature Communications, 2018 Reliable inference of gene interactions from perturbation experiments remains a challenge. Here, the authors quantify the upper limits of transcriptional network inference from knockout screens, identify the key determinants of accuracy, and introduce an
C. F. Blum +3 more
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A Mathematical Model of a Micrometastasis [PDF]
Computational and Mathematical Methods in Medicine, 1997 Experimental evidence indicates that tumour metastases can exist for long periods in a dormant state, with cell proliferation balancing cell death. However, this balance can be upset, by removing the primary tumour for instance, which causes the metastasis to grow, or by adminstering a substances inhabiting angiogenesis which causes the metastasis toi ...
Malcolm Bloor, Michael Wilson
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Prevention of Surgical Site Infections: Decontamination With Mupirocin Based on Preoperative Screening for Staphylococcus aureus Carriers or Universal Decontamination? [PDF]
, 2016 Perioperative decolonization of Staphylococcus aureus nasal carriers with mupirocin together with chlorhexidine body washing reduces the incidence of S. aureus surgical site infection. A targeted strategy, applied in S.
Mathematical Modeling +4 more
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
On Jupiter and his Galilean satellites: Librations of De Sitter's periodic motions [PDF]
, 2016 The motion of Jupiter's four Galilean satellites Io–Europa–Ganymedes–Callisto is subjected to an orbital 1:2:4–resonance of the former (and inner) three.
Broer, Henk W. +6 more
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FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Open MathematicsIn this study, a multipoint boundary value problem for Volterra-Fredholm integro-differential equations is considered. The addition of a new function converts the system of Volterra-Fredholm integro-differential equations to a system of Fredholm integro ...
Bakirova Elmira A. +2 more
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Pitchfork–Hopf bifurcations in 1D neural field models with transmission delays [PDF]
, 2015 Recently, local bifurcation theory for delayed neural fields was developed. In this paper, we show how symmetry arguments and residue calculus can be used to simplify the computation of the spectrum in special cases and the evaluation of the normal form ...
Dijkstra, K. +6 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Stochastic programming framework for Lithuanian pension payout modelling
Croatian Operational Research Review, 2014 The paper provides a scientific approach to the problem of selecting a pension fund by taking into account some specific characteristics of the Lithuanian Republic (LR) pension accumulation system.
Audrius Kabašinskas +3 more
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