Results 51 to 60 of about 26,169,234 (336)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Nature Communications, 2018 Reliable inference of gene interactions from perturbation experiments remains a challenge. Here, the authors quantify the upper limits of transcriptional network inference from knockout screens, identify the key determinants of accuracy, and introduce an
C. F. Blum +3 more
doaj +1 more source
Introduction to papers on the modeling and analysis of network data [PDF]
, 2010 Introduction to papers on the modeling and analysis of network dataComment: Published in at http://dx.doi.org/10.1214/10-AOAS346 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www ...
Fienberg, Stephen E.
core +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
MathematicsThis paper examines the relationship between weak orthogonality and almost orthogonality for complete non-algebraic 1-types in weakly ordered minimal theories.
Bektur Baizhanov +2 more
doaj +1 more source
Numerical method for solving multipoints elliptic-parabolic equation for dehydration process [PDF]
, 2012 Drying is the oldest and efficient form of preserving fruits. This research focuses on the mathematical modeling of tropical fruits dehydration using instant controlled pressure drop (Détente Instantanée Controlée or known as DIC) technique.
Alias, Norma +2 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Stochastic programming framework for Lithuanian pension payout modelling
Croatian Operational Research Review, 2014 The paper provides a scientific approach to the problem of selecting a pension fund by taking into account some specific characteristics of the Lithuanian Republic (LR) pension accumulation system.
Audrius Kabašinskas +3 more
doaj +1 more source
On a boundary value problem for a Boussinesq-type equation in a triangle
Вестник КазНУ. Серия математика, механика, информатика, 2022 Earlier, we considered an initial-boundary value problem for a one-dimensional Boussinesq-type equation in a domain that is a trapezoid, in which the theorems on its unique weak solvability in Sobolev classes were established by the methods of the theory
M. T. Jenaliyev +2 more
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source