Results 61 to 70 of about 327,393 (318)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
A Moving Mesh Finite Difference Method for Non-Monotone Solutions of Non-Equilibrium Equations in Porous Media [PDF]
, 2017 An adaptive moving mesh finite difference method is presented to solve two types of equations with dynamic capillary pressure effect in porous media. One is the non-equilibrium Richards Equation and the other is the modified Buckley-Leverett equation ...
Paul Andries Zegeling +5 more
core +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Beeldreconstructie in MRI met compressed sensing [PDF]
, 2016 Philips Healthcare is een van de grootste fabrikanten van MRI-scanners ter wereld en is geïnteresseerd in het gebruik van compressed sensing-technieken om MRI-scans te versnellen.
Mathematical Modeling +2 more
core
Multiple expansions of real numbers with digits set { 0 , 1 , q} [PDF]
, 2019 For q> 1 we consider expansions in base q with digits set { 0 , 1 , q}. Let U q be the set of points which have a unique q-expansion. For k= 2 , 3 , … , ℵ let B k be the set of bases q> 1 for which there exists x having precisely k different q-expansions,
Jiang, Kan +5 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
On an Inverse Problem of Reconstructing a Heat Conduction Process from Nonlocal Data
Advances in Mathematical Physics, 2018 We consider an inverse problem for a one-dimensional heat equation with involution and with periodic boundary conditions with respect to a space variable.
Makhmud A. Sadybekov +2 more
doaj +1 more source
Mathematical Models of Consciousness [PDF]
Entropy, 2020 In recent years, promising mathematical models have been proposed that aim to describe conscious experience and its relation to the physical domain. Whereas the axioms and metaphysical ideas of these theories have been carefully motivated, their mathematical formalism has not. In this article, we aim to remedy this situation. We give an account of what
openaire +4 more sources
Mathematical Modelling in Neuroendocrinology [PDF]
Journal of Neuroendocrinology, 2008 In neuroendocrinology, mathematical modelling is about formalising our understanding of the behaviour of the complex biological systems with which we deal. Formulating our explanations mathematically ensures their logical consistency, and makes them open to structured analysis; it is a stringent test of their intellectual coherence.
G, Leng, D J, Macgregor
openaire +2 more sources
Enhancing the robustness of a multiplex network leads to multiple discontinuous percolation transitions [PDF]
, 2019 Determining design principles that boost the robustness of interdependent networks is a fundamental question of engineering, economics, and biology. It is known that maximizing the degree correlation between replicas of the same node leads to optimal ...
Mathematical Modeling +5 more
core +1 more source