Results 21 to 30 of about 82,948 (266)

Mathematical model of sarcoidosis [PDF]

Proceedings of the National Academy of Sciences, 2014
Significance Sarcoidosis is a disease involving abnormal collection of granulomas that develop in the lung and other organs. The origin of the disease is unknown, clinical data are very limited, and there is no current effective treatment.
Wenrui, Hao, Elliott D, Crouser, Avner, Friedman   +2 more
openaire   +2 more sources

Quarantine and testing strategies in contact tracing for SARS-CoV-2: a modelling study

The Lancet Public Health, 2021
Summary: Background: In most countries, contacts of confirmed COVID-19 cases are asked to quarantine for 14 days after exposure to limit asymptomatic onward transmission.
Billy J Quilty, MSc, Samuel Clifford, PhD, Joel Hellewell, PhD, Timothy W Russell, PhD, Adam J Kucharski, PhD, Stefan Flasche, ProfPhD, W John Edmunds, ProfPhD, Katherine E Atkins, Anna M Foss, Naomi R Waterlow, Kaja Abbas, Rachel Lowe, Carl A B Pearson, Sebastian Funk, Alicia Rosello, Gwenan M Knight, Nikos I Bosse, Simon R Procter, Georgia R Gore-Langton, Alicia Showering, James D Munday, Katharine Sherratt, Thibaut Jombart, Emily S Nightingale, Yang Liu, Christopher I Jarvis, Graham Medley, Oliver Brady, Hamish P Gibbs, David Simons, Jack Williams, Damien C Tully, Stefan Flasche, Sophie R Meakin, Kevin Zandvoort, Fiona Y Sun, Mark Jit, Petra Klepac, Matthew Quaife, Rosalind M Eggo, Frank G Sandmann, Akira Endo, Kiesha Prem, Sam Abbott, Rosanna Barnard, Yung-Wai D Chan, Megan Auzenbergs, Amy Gimma, C Julian Villabona-Arenas, Nicholas G Davies   +49 more
doaj   +1 more source

SARS-CoV-2 infection risk during delivery of childhood vaccination campaigns: a modelling study

BMC Medicine, 2021
Background The COVID-19 pandemic has disrupted the delivery of immunisation services globally. Many countries have postponed vaccination campaigns out of concern about infection risks to the staff delivering vaccination, the children being vaccinated ...
Simon R. Procter, Kaja Abbas, Stefan Flasche, Ulla Griffiths, Brittany Hagedorn, Kathleen M. O’Reilly, CMMID COVID-19 Working Group, Mark Jit   +7 more
doaj   +1 more source

Disentangling the Information in Species Interaction Networks

Entropy, 2021
Shannon’s entropy measure is a popular means for quantifying ecological diversity. We explore how one can use information-theoretic measures (that are often called indices in ecology) on joint ensembles to study the diversity of species interaction ...
Michiel Stock, Laura Hoebeke, Bernard De Baets   +2 more
doaj   +1 more source

Correspondence to: Estimating the full health and economic benefits of current and future influenza vaccines

BMC Medicine, 2023
We recently published an article in BMC Medicine looking at the potential health and economic impact of paediatric vaccination using next-generation influenza vaccines in Kenya: a modelling study.
Naomi R. Waterlow, Simon R. Procter, Rosalind M. Eggo, Mark Jit   +3 more
doaj   +1 more source

Forecasting SARS-CoV-2 epidemic dynamic in Poland with the pDyn agent-based model

Epidemics
We employ pDyn (derived from “pandemics dynamics”), an agent-based epidemiological model, to forecast the fourth wave of the SARS-CoV-2 epidemic, primarily driven by the Delta variant, in Polish society.
Karol Niedzielewski, Rafał P. Bartczuk, Natalia Bielczyk, Dominik Bogucki, Filip Dreger, Grzegorz Dudziuk, Łukasz Górski, Magdalena Gruziel-Słomka, Jędrzej Haman, Artur Kaczorek, Jan Kisielewski, Bartosz Krupa, Antoni Moszyński, Jędrzej M. Nowosielski, Maciej Radwan, Marcin Semeniuk, Urszula Tymoszuk, Jakub Zieliński, Franciszek Rakowski   +18 more
doaj   +1 more source

Modeling Patterns of Population Exposure With a Multiscale Framework Utilizing LOTOS‐EUROS Chemical Transport Model, Mobility Surveys and Particulate Toxicity

GeoHealth
The present study proposes a high‐resolution, multi‐component framework to estimate human exposure to air pollution in tropical urban environments, addressing complex topography and limited historical mobility and exposure data. This framework is applied
Valeria Solórzano‐Araque, Andrés Yarce Botero, Jhon Edinson Hinestroza‐Ramirez, Fernando Fernandez‐Restrepo, Sebastian Carmona Estrada, Pablo Alberto Osorio‐Marulanda, Lisseth Cruz‐Ruiz, Santiago Isaza‐Cadavid, O. L. Quintero   +8 more
doaj   +1 more source

Detecting Underwater Concrete Cracks with Machine Learning: A Clear Vision of a Murky Problem

Applied Sciences, 2023
This paper presents the development of an underwater crack detection system for structural integrity assessment of submerged structures, such as offshore oil and gas installations, underwater pipelines, underwater foundations for bridges, dams, etc.
Ugnė Orinaitė, Viltė Karaliūtė, Mayur Pal, Minvydas Ragulskis   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source