Results 61 to 70 of about 1,385,828 (305)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

Visualization as an Intuitive Process in Mathematical Practice

open access: yesConatus - Journal of Philosophy
In the field of the philosophy of mathematics, in recent years, there has been a resurgence of two processes: intuition and visualization. History has shown us that great mathematicians in their inventions have used these processes to arrive at their ...
Lina María Peña-Páez
doaj   +1 more source

A naturalistic justification of the generic multiverse with a core [PDF]

open access: yes, 2018
In this paper, I argue that a naturalist approach in philosophy of mathematics justifies a pluralist conception of set theory. For the pluralist, there is not a Single Universe, but there is rather a Multiverse, composed by a plurality of universes ...
de Ceglie, Matteo
core  

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +9 more
wiley   +1 more source

Stress in Chinese teachers who teach the mathematically gifted: a qualitative perspective

open access: yesFrontiers in Psychology
Those who teach mathematically gifted high school students play a key role in both their identification and cultivation. Teachers who teach the Mathematical Olympiad in China work long hours and teach difficult content; they are under a significant ...
Sunzhong Lv   +6 more
doaj   +1 more source

The Physician‐Scientist Pipeline for Pediatric Rheumatology – Current Landscape and Future Perspectives.

open access: yesArthritis Care &Research, Accepted Article.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu   +2 more
wiley   +1 more source

Formalizability and Knowledge Ascriptions in Mathematical Practice

open access: yesPhilosophia Scientiæ, 2009
We investigate the truth conditions of knowledge ascriptions for the case of mathematical knowledge. The availability of a formalizable mathematical proof appears to be a natural criterion:(*) X knows that p is true iff X has available a formalizable ...
Eva Müller-Hill
doaj   +1 more source

Why Numbers Are Sets [PDF]

open access: yes, 2002
I follow standard mathematical practice and theory to argue that the natural numbers are the finite von Neumann ordinals. I present the reasons standardly given for identifying the natural numbers with the finite von Neumann's.
Steinhart, Eric
core  

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg   +5 more
wiley   +1 more source

Culture, goal orientation and achievement of vocational college students

open access: yesFrontiers in Psychology
IntroductionThis study explored the relationship between cultural values, goal orientation, and mathematics achievement in mainland China.MethodsStructural equation modelling was used to analyze data collected from 1,004 first-year students of four ...
Xuefei Lin   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy