Results 41 to 50 of about 176,536 (262)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Statistical Analysis of Inverse Weibull based on Step-Stress Partially Accelerated Life Tests with Unified Hybrid Censoring Data

Computational Journal of Mathematical and Statistical Sciences
Accelerated life testing (ALT) is a primary method for rapidly evaluating product reliability. This paper focuses on statistical inference for the invertedWeibull distribution under a step-stress partially ALT (SSPALT) model with a unified hybrid ...
Amal Soliman Hassan, Abd ELwahab Hagag, Nader Metwally, Omar Hussein Sery   +3 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Age and gender patterns in emergency alarms and missions: a cross-sectional observational study

BMC Emergency Medicine
Background Emergency medical services play a key role in the healthcare system. An ageing population, economic challenges, and technological advances require emergency prehospital care to be flexible, efficient, and equal.
Kean Tang, Veronica Lindström, Markus Ådahl, Patrik Rydén   +3 more
doaj   +1 more source

Novel Investigation of Multivariable Conformable Calculus for Modeling Scientific Phenomena

Journal of Mathematics, 2021
New investigation on the conformable version (CoV) of multivariable calculus is proposed. The conformable derivative (CoD) of a real-valued function (RVF) of several variables (SVs) and all related properties are investigated.
Mohammed K. A. Kaabar, Francisco Martínez, Inmaculada Martínez, Zailan Siri, Silvestre Paredes   +4 more
doaj   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, Accepted Article.
Objective VEXAS syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures. A VEXAS‐specific disease activity index (DAI) is an essential tool for reliably capturing changes in disease ...
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

The study of the stability of asphalt concrete mixture composition optimization mathematical models using imitative simulation

Transport, 2003
The method of statistical imitative simulation (Monte-Carlo) was used to simulate the heterogeneity of the produced asphalt concrete mixture (ACM) mineral part grading.
Valentinas Podviezko, Henrikas Sivilevičius   +1 more
doaj   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

The Flexible Fréchet Distribution: Properties, Inference, and Medical Applications

Journal of Mathematics
This paper introduces the Marshall–Olkin Weibull–Fréchet (MOWFr) distribution, a modified form of the Fréchet model that demonstrates improved fitting capabilities compared to established generalizations.
Ahmed Z. Afify, Ekramy A. Hussein, Hazem Al-Mofleh, Rehab Alsultan, Hassan M. Aljohani   +4 more
doaj   +1 more source